Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | STAT3 | P40763 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3307798 | 0.86 | KMT2A (0.74) | KMT2AMEN1HDAC1HDAC2HDAC8 | |
| SCHEMBL8531490 | 0.85 | KMT2A (0.68) | KMT2AMEN1HDAC1HDAC2HDAC8 | |
| SCHEMBL10165370 | 0.83 | KMT2A (0.66) | KMT2AMEN1HDAC1HDAC2HDAC8 | |
| SCHEMBL10203422 | 0.83 | KMT2A (0.66) | KMT2AMEN1HDAC1HDAC2HDAC8 | |
| SCHEMBL8531844 | 0.82 | GAA (0.69) | KMT2AMEN1HDAC1HDAC2HDAC8 | |
| SCHEMBL6224417 | 0.82 | KMT2A (1.00) | KMT2AMEN1HDAC1HDAC2HDAC8 | |
| SCHEMBL8532599 | 0.82 | KMT2A (0.64) | KMT2AMEN1HDAC1HDAC2HDAC8 | |
| SCHEMBL8530608 | 0.81 | KMT2A (0.48) | KMT2AMEN1SMN1; SMN2RAB9AHTT | |
| SCHEMBL9703067 | 0.81 | KMT2A (0.48) | KMT2AMEN1SMN1; SMN2RAB9AHTT | |
| SCHEMBL8528645 | 0.81 | ALDH1A1 (0.71) | KMT2AMEN1SMN1; SMN2RAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460679-B1 | Endothelin antagonistic peptide derivatives | BANYU PHARMA CO LTD (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5691315-A | CARDIOVASCULAR DISORDERS; VASODILATOR; BRONCHODILATOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5470833-A | Vasodilators, bronchodilators | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |