SCHEMBL8530855

SCHEMBL8530855

C=CC(=O)OC1(OC(=O)C=C)CC1

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.37
TP53 P04637 3/20 0.37
HIF1A Q16665 3/20 0.37
CYP3A4 P08684 2/20 0.37
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TSHR P16473 7/20 0.36
HSD17B10 Q99714 1/20 0.36
HPGD P15428 1/20 0.32
LMNA P02545 1/20 0.32
FGFR4 P22455 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL786273 0.88 ALDH1A1 (0.33) ALDH1A1TP53HIF1ACYP3A4MAPK1
Ammonia Solution, Strong SCHEMBL28151278 0.82 TSHR (0.35) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL19886283 0.78 TSHR (0.31) TSHRHPGD
SCHEMBL14642989 0.77
SCHEMBL10994832 0.77 TSHR (0.31) TSHR
SCHEMBL89714 0.75 TSHR (0.33) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL19427474 0.75
SCHEMBL7912501 0.75 TSHR (0.38) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL7912504 0.75 TSHR (0.38) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL3679550 0.73 TSHR (0.32) ALDH1A1TP53HIF1ACYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12036774-B2 Elastomeric chemical barrier articles Ansell Limited (AU) 2024-07-16 US disclosed
CN-113454153-B In-line ultrasonic inspection for detecting partial vulcanization of rubber mixtures in-situ silylation of light-colored fillers 朗盛德国有限责任公司 2023-04-28 CN disclosed
US-20220194061-A1 ELASTOMERIC CHEMICAL BARRIER ARTICLES Ansell Limited (AU) 2022-06-23 US disclosed
EP-3966035-A1 ELASTOMERIC CHEMICAL BARRIER ARTICLES Ansell Limited (AU) 2022-03-16 EP disclosed
CN-108603000-B Method for testing in situ silanization of bright fillers 朗盛德国有限责任公司 2021-10-01 CN disclosed
CN-113454153-A On-line ultrasonic inspection for detecting partial vulcanization of rubber mixtures in-situ silanization of light-colored fillers 朗盛德国有限责任公司 2021-09-28 CN disclosed
WO-2020223756-A1 ELASTOMERIC CHEMICAL BARRIER ARTICLES Ansell Limited (AU) 2020-11-12 WO disclosed
EP-0656043-B1 PLASTIC CLOSURE LINERS AND CLOSURES SHELL OIL CO (US) 1998-10-14 EP disclosed
US-5486558-A POLYMER BLEND, FOR POLYETHYLENE TEREPHTHALATE BOTTLES SHELL OIL COMPANY (US) 1996-01-23 US disclosed
EP-0656043-A1 PLASTIC CLOSURE LINERS AND CLOSURES SHELL OIL COMPANY (US) 1995-06-07 EP disclosed
WO-1995000599-A2 PLASTIC CLOSURES AND CLOSURE LINERS SHELL OIL COMPANY (US) 1995-01-05 WO disclosed