Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9031190 | 0.85 | ALDH1A1 (0.49) | KDM4EHSD17B10ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5595068 | 0.84 | AKR1C4 (0.53) | KDM4EHSD17B10AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL3576620 | 0.83 | KDM4E (0.53) | KDM4EHSD17B10AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL28794509 | 0.81 | AKR1C4 (0.55) | KDM4EHSD17B10AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL28105089 | 0.81 | ALDH1A1 (0.52) | KDM4EHSD17B10ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL17799568 | 0.79 | KDM4E (0.49) | KDM4EHSD17B10AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL28091444 | 0.78 | AKR1C4 (0.47) | KDM4EHSD17B10AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL5950237 | 0.78 | DHODH (0.57) | KDM4EAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL10892245 | 0.78 | RAPGEF4 (0.52) | HSD17B10ALDH1A1SMN1; SMN2TSHRMEN1 | |
| Hydrochloric Acid SCHEMBL17799576 | 0.78 | KDM4E (0.48) | KDM4EHSD17B10AKR1C4AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105906502-A | Preparation method of 3,5-dichlorobenzoyl chloride | 山东润博生物科技有限公司 | 2016-08-31 | — | — | CN | claimed |
| CN-105906502-A | Preparation method of 3,5-dichlorobenzoyl chloride | 山东润博生物科技有限公司 | 2016-08-31 | — | — | CN | disclosed |
| CN-105906502-A | Preparation method of 3,5-dichlorobenzoyl chloride | 山东润博生物科技有限公司 | 2016-08-31 | — | — | CN | disclosed |
| CN-105837432-A | Novel preparation method of 3,5-dichlorobenzoyl chloride | 山东润博生物科技有限公司 | 2016-08-10 | — | — | CN | disclosed |
| US-5783577-A | COMBINATORIAL LIBRARY FOR DRUG SCREENING | TREGA BIOSCIENCES, INC. (US) | 1998-07-21 | — | — | US | disclosed |
| WO-1998011438-A1 | SYNTHESIS OF QUINAZOLINONE LIBRARIES AND DERIVATIVES THEREOF | TREGA BIOSCIENCES, INC. (US) | 1998-03-19 | — | — | WO | disclosed |
| WO-1997010221-A1 | SYNTHESIS OF QUINAZOLINONE LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1997-03-20 | — | — | WO | disclosed |