SCHEMBL8530919

SCHEMBL8530919

Cl[Ru]Cl.Fc1ccc(P(c2ccc(F)cc2)c2ccc(F)cc2)cc1.Fc1ccc(P(c2ccc(F)cc2)c2ccc(F)cc2)cc1.Fc1ccc(P(c2ccc(F)cc2)c2ccc(F)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CA1 P00915 4/20 0.35
CA2 P00918 4/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
ACHE P22303 1/20 0.35
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
IDO1 P14902 1/20 0.31
ORAI1 Q96D31 1/20 0.31
ORAI2 Q96SN7 1/20 0.31
ORAI3 Q9BRQ5 1/20 0.31
TRPV6 Q9H1D0 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
LOXL2 Q9Y4K0 1/20 0.31
PTPN1 P18031 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196718 0.88 CYP3A4 (0.44) CYP3A4TDP1CA1CA2CA7
Bromide SCHEMBL28417395 0.85 CYP3A4 (0.42) CYP3A4TDP1CA1CA2CA7
SCHEMBL5713320 0.85 CYP3A4 (0.42) CYP3A4TDP1CA1CA2CA7
SCHEMBL31328588 0.83 CYP3A4 (0.36) CYP3A4TDP1CA1CA2CA7
Hydrochloric Acid SCHEMBL21724713 0.82 CYP3A4 (0.40) CYP3A4TDP1CA1CA2CA7
SCHEMBL18702923 0.78 CYP3A4 (0.67) CYP3A4TDP1CA1CA2CA7
SCHEMBL2543676 0.78 CYP3A4 (0.67) CYP3A4TDP1CA1CA2CA7
SCHEMBL10874458 0.78 CYP3A4 (0.67) CYP3A4TDP1CA1CA2CA7
SCHEMBL17563446 0.76 ACHE (0.68) TDP1ACHE
Water SCHEMBL27604157 0.76 CYP3A4 (0.63) CYP3A4TDP1CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0713846-B1 PROCESS FOR PRODUCING CYCLOALKANOL AND CYCLOALKANONE UBE INDUSTRIES (JP) 1998-10-28 EP claimed
US-5728890-A DECOMPOSING CYCLOALKYLHYDROPEROXIDE BY CONTACT WITH A RUTHENIUM COMPLEX UBE INDUSTRIES, LTD. (JP) 1998-03-17 US claimed
EP-0713846-A1 PROCESS FOR PRODUCING CYCLOALKANOL AND CYCLOALKANONE UBE INDUSTRIES, LTD. (JP) 1996-05-29 EP claimed
EP-0713846-B1 PROCESS FOR PRODUCING CYCLOALKANOL AND CYCLOALKANONE UBE INDUSTRIES (JP) 1998-10-28 EP disclosed
US-5728890-A DECOMPOSING CYCLOALKYLHYDROPEROXIDE BY CONTACT WITH A RUTHENIUM COMPLEX UBE INDUSTRIES, LTD. (JP) 1998-03-17 US disclosed
EP-0713846-A1 PROCESS FOR PRODUCING CYCLOALKANOL AND CYCLOALKANONE UBE INDUSTRIES, LTD. (JP) 1996-05-29 EP disclosed