Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.31 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.31 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.31 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196718 | 0.88 | CYP3A4 (0.44) | CYP3A4TDP1CA1CA2CA7 | |
| SCHEMBL5713320 | 0.85 | CYP3A4 (0.42) | CYP3A4TDP1CA1CA2CA7 | |
| Bromide SCHEMBL28417395 | 0.85 | CYP3A4 (0.42) | CYP3A4TDP1CA1CA2CA7 | |
| SCHEMBL8530919 | 0.83 | CYP3A4 (0.36) | CYP3A4TDP1CA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL21724713 | 0.82 | CYP3A4 (0.40) | CYP3A4TDP1CA1CA2CA7 | |
| SCHEMBL10874458 | 0.78 | CYP3A4 (0.67) | CYP3A4TDP1CA1CA2CA7 | |
| SCHEMBL18702923 | 0.78 | CYP3A4 (0.67) | CYP3A4TDP1CA1CA2CA7 | |
| SCHEMBL2543676 | 0.78 | CYP3A4 (0.67) | CYP3A4TDP1CA1CA2CA7 | |
| SCHEMBL17563446 | 0.76 | ACHE (0.68) | TDP1ACHE | |
| SCHEMBL16459655 | 0.74 | FBP1 (0.43) | CYP3A4TDP1CA1CA2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12187747-B2 | Gold compositions and methods of use thereof | UNIVERSITY OF MASSACHUSETTS (US) | 2025-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12187747-B2 | Gold compositions and methods of use thereof | LSS, LGALS7; LGALS7B, LGALS3 | CYP3A4 128/4885TDP1 2830/4885CA1 2077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.