Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18709047 | 0.78 | ALDH1A1 (0.39) | MAPTKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL27759679 | 0.70 | MAPT (0.48) | MAPTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL8459429 | 0.70 | PDCD1 (0.50) | MAPTKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL11383927 | 0.69 | GABRA1 (0.40) | MAPTKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL980893 | 0.68 | GABRA1 (0.50) | KDM4EALDH1A1HPGDHSD17B10GABRA1 | |
| SCHEMBL29047890 | 0.68 | GABRA1 (0.40) | MAPTKDM4EALDH1A1HPGDCYP1A2 | |
| Phosphine SCHEMBL9579776 | 0.68 | PDCD1 (0.48) | MAPTKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL30481171 | 0.68 | GABRA1 (0.40) | MAPTKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL6278707 | 0.68 | KDM4E (0.43) | MAPTKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL1786392 | 0.67 | GABRA1 (0.39) | MAPTKDM4EALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733610-B1 | Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device | CHISSO CORP (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5635108-A | A HEXYNEDIENE DERIVATIVE | CHISSO CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0733610-A1 | Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device | Chisso Corporation (JP) | 1996-09-25 | — | — | EP | disclosed |