SCHEMBL853165

SCHEMBL853165

NC(=O)c1nc2ncccc2[nH]1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 1/20 0.58
DAGLA Q9Y4D2 1/20 0.51
HPSE Q9Y251 1/20 0.49
PDE10A Q9Y233 2/20 0.48
KDM4E B2RXH2 2/20 0.48
CYP1A2 P05177 2/20 0.48
MAPT P10636 2/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
PDE5A O76074 2/20 0.47
METAP1 P53582 2/20 0.47
METAP2 P50579 1/20 0.47
KMT2A Q03164 1/20 0.47
ALDH1A1 P00352 2/20 0.45
CYP2D6 P10635 1/20 0.45
ATM Q13315 1/20 0.45
PRMT5 O14744 1/20 0.44
FGFR1 P11362 1/20 0.43
FLT1 P17948 1/20 0.43
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30943978 1.00 NUDT1 (0.58) NUDT1DAGLAHPSEPDE10AKDM4E
SCHEMBL27832091 0.85 PDE10A (0.57) NUDT1DAGLAHPSEPDE10AKDM4E
SCHEMBL2291563 0.84 DAGLA (0.56) NUDT1DAGLAHPSEPDE10AKDM4E
SCHEMBL29623058 0.84 DAGLA (0.56) NUDT1DAGLAHPSEPDE10AKDM4E
SCHEMBL24112427 0.82 NUDT1 (0.53) NUDT1DAGLAHPSEPDE10AKDM4E
SCHEMBL2079832 0.81 DAGLA (0.53) NUDT1DAGLAHPSEPDE10AKDM4E
SCHEMBL28565451 0.79 NUDT1 (0.50) NUDT1DAGLAHPSEPDE10AKDM4E
SCHEMBL6246031 0.79 NUDT1 (0.50) NUDT1DAGLAHPSEPDE10AKDM4E
SCHEMBL3247997 0.78 HCAR2 (0.55) AURKA
SCHEMBL24450253 0.78 DAGLA (0.58) NUDT1DAGLAHPSEPDE10AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12279617-B2 Agricultural and horticultural chemical agent containing new imidazopyridine-2-carboxamide derivative as active ingredient AGRO-KANESHO CO., LTD. (JP) 2025-04-22 US claimed
EP-3985004-B1 AGRICULTURAL AND HORTICULTURAL CHEMICAL AGENT CONTAING NEW IMIDAZOPYRIDINE-2-CARBOXAMIDE DERIVATIVE AS ACTIVE INGREDIENT AGRO KANESHO CO LTD (JP) 2024-09-04 EP claimed
CN-114008045-B Agricultural and horticultural agent containing novel imidazopyridine-2-carboxamide derivative as active ingredient 阿格罗-金正株式会社 2024-07-16 CN claimed
US-20220330550-A1 AGRICULTURAL AND HORTICULTURAL CHEMICAL AGENT CONTAINING NEW IMIDAZOPYRIDINE-2-CARBOXAMIDE DERIVATIVE AS ACTIVE INGREDIENT AGRO-KANESHO CO., LTD. (JP) 2022-10-20 US claimed
EP-3985004-A1 AGRICULTURAL AND HORTICULTURAL CHEMICAL AGENT HAVING NOVEL IMIDAZOPYRIDINE-2-CARBOXAMIDE DERIVATIVE AS ACTIVE INGREDIENT Agro-Kanesho Co., Ltd. (JP) 2022-04-20 EP claimed
CN-114008045-A Agrohorticultural agent containing novel imidazopyridine-2-carboxamide derivative as active ingredient 阿格罗-金正株式会社 2022-02-01 CN claimed
WO-2020251013-A1 AGRICULTURAL AND HORTICULTURAL CHEMICAL AGENT HAVING NOVEL IMIDAZOPYRIDINE-2-CARBOXAMIDE DERIVATIVE AS ACTIVE INGREDIENT アグロカネショウ株式会社 2020-12-17 WO claimed
EP-1684736-B1 DNA DAMAGE REPAIR INHIBITORS FOR TREATMENT OF CANCER KUDOS PHARM LTD (GB) 2011-08-24 EP claimed
US-12279617-B2 Agricultural and horticultural chemical agent containing new imidazopyridine-2-carboxamide derivative as active ingredient AGRO-KANESHO CO., LTD. (JP) 2025-04-22 US disclosed
US-12279617-B2 Agricultural and horticultural chemical agent containing new imidazopyridine-2-carboxamide derivative as active ingredient AGRO-KANESHO CO., LTD. (JP) 2025-04-22 US disclosed
US-12279617-B2 Agricultural and horticultural chemical agent containing new imidazopyridine-2-carboxamide derivative as active ingredient AGRO-KANESHO CO., LTD. (JP) 2025-04-22 US disclosed
EP-3985004-B8 AGRICULTURAL AND HORTICULTURAL CHEMICAL AGENT CONTAING NEW IMIDAZOPYRIDINE-2-CARBOXAMIDE DERIVATIVE AS ACTIVE INGREDIENT AGRO KANESHO CO LTD (JP) 2024-10-09 EP disclosed
EP-4423097-A1 IMIDAZOPYRIDINE AMIDES AND RELATED COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS Janssen Sciences Ireland Unlimited Company (IE) 2024-09-04 EP disclosed
EP-3985004-C0 AGRICULTURAL AND HORTICULTURAL CHEMICAL AGENT CONTAING NEW IMIDAZOPYRIDINE-2-CARBOXAMIDE DERIVATIVE AS ACTIVE INGREDIENT AGRO KANESHO CO LTD (JP) 2024-09-04 EP disclosed
WO-2008020180-A2 METHODS OF INCREASING THE SENSITIVITY OF CANCER CELLS TO DNA DAMAGE KUDOS PHARMACEUTICALS LIMITED (GB) 2008-02-21 WO disclosed
WO-2008003856-A1 DERIVATIVES OF IMIDAZO[1,2-A]PYRIDINE-2-CARBOXAMIDES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS SANOFI-AVENTIS (FR) 2008-01-10 WO disclosed
EP-1684736-A1 DNA DAMAGE REPAIR INHIBITORS FOR TREATMENT OF CANCER Kudos Pharmaceuticals Limited (GB) 2006-08-02 EP disclosed
US-20060142231-A1 DNA damage repair inhibitors for treatment of cancer KUDOS PHARMACEUTICALS LIMITED (GB) 2006-06-29 US disclosed
US-20050227919-A1 DNA damage repair inhibitors for the treatment of cancer KUDOS PHARMACEUTICALS LIMITED 2005-10-13 US disclosed
WO-2005053662-A1 DNA DAMAGE REPAIR INHIBITORS FOR TREATMENT OF CANCER KUDOS PHARMACEUTICALS LIMITED (GB) 2005-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12279617-B2 Agricultural and horticultural chemical agent containing new imidazopyridine-2-carboxamide derivative as active ingredient CBR3, HRH4, H1-0 NUDT1 1043/4885DAGLA 2985/4885HPSE 3800/4885
US-20060142231-A1 DNA damage repair inhibitors for treatment of cancer MRE11, PARP2, ERCC4 NUDT1 226/4885DAGLA 4405/4885HPSE 2283/4885
US-20050227919-A1 DNA damage repair inhibitors for the treatment of cancer MRE11, ERCC4, PARP2 NUDT1 194/4885DAGLA 4494/4885HPSE 2294/4885
US-20220330550-A1 AGRICULTURAL AND HORTICULTURAL CHEMICAL AGENT CONTAINING NEW IMIDAZOPYRIDINE-2-CARBOXAMIDE DERIVATIVE AS ACTIVE INGREDIENT CBR3, HRH4, H1-0 NUDT1 1070/4885DAGLA 3606/4885HPSE 3717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.