SCHEMBL853181

SCHEMBL853181

CC(C)(C)N1CCC(NC(=O)O)CC1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
EPHX2 P34913 6/20 0.40
SIGMAR1 Q99720 1/20 0.39
EPHX1 P07099 4/20 0.38
LMNA P02545 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
WNT1 P04628 1/20 0.36
DYRK1A Q13627 1/20 0.36
SSTR4 P31391 1/20 0.35
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL743576 0.89 CTSK (0.39) ALDH1A1EPHX2SIGMAR1LMNANPSR1
SCHEMBL1265815 0.89 CTSK (0.39) ALDH1A1EPHX2SIGMAR1LMNANPSR1
SCHEMBL1487188 0.89 CTSK (0.39) ALDH1A1EPHX2SIGMAR1LMNANPSR1
SCHEMBL10205072 0.84 EPHX2 (0.44) ALDH1A1EPHX2SIGMAR1EPHX1KDM4E
SCHEMBL12539777 0.82 ALDH1A1 (0.34) ALDH1A1EPHX2SIGMAR1EPHX1LMNA
SCHEMBL14263081 0.82 ALDH1A1 (0.62) ALDH1A1EPHX2SIGMAR1EPHX1LMNA
SCHEMBL27938687 0.82 ALDH1A1 (0.41) ALDH1A1EPHX2SIGMAR1EPHX1LMNA
SCHEMBL17889938 0.82 ALDH1A1 (0.38) ALDH1A1EPHX2SIGMAR1EPHX1LMNA
SCHEMBL16418439 0.81 CTSK (0.42) ALDH1A1EPHX2SIGMAR1EPHX1WNT1
SCHEMBL10205067 0.81 POLB (0.48) ALDH1A1EPHX2LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115028661-A 4-aminopiperidine-1-methyl phosphate and preparation method thereof 上海应用技术大学 2022-09-09 CN claimed
CN-117062813-B Polycyclic compound and application thereof 四川汇宇制药股份有限公司 2026-05-19 CN disclosed
EP-4739671-A1 NEW COMPOUNDS Aston University (GB) 2026-05-13 EP disclosed
CN-120152967-A Bifunctional compounds containing 2, 5-substituted pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway 霖康疗法公司 2025-06-13 CN disclosed
CN-115943144-B Compound serving as PAK4 kinase inhibitor and preparation method and application thereof 成都海博为药业有限公司 2025-05-13 CN disclosed
CN-113423708-B Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists 百济神州有限公司 2025-04-22 CN disclosed
CN-119816484-A Novel piperazine derivative or salt thereof and pharmaceutical composition 富士胶片株式会社 2025-04-11 CN disclosed
CN-113454086-B Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists 百济神州有限公司 2025-03-14 CN disclosed
CN-119306700-A DNMT1-HDAC double-target inhibitor and preparation method and application thereof 山东大学 2025-01-14 CN disclosed
WO-2025008627-A1 NEW COMPOUNDS ASTON UNIVERSITY (GB) 2025-01-09 WO disclosed
WO-2006096444-A2 CHEMICAL COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2006-09-14 WO disclosed
EP-1605938-A2 ANTIBACTERIAL AGENTS GLAXO GROUP LIMITED (GB) 2005-12-21 EP disclosed
EP-1583537-A3 PIPERIDINE COMPOUNDS AS ANTIBACTERIALS GLAXO GROUP LIMITED (GB) 2005-12-14 EP disclosed
EP-1583537-A2 PIPERIDINE COMPOUNDS AS ANTIBACTERIALS GLAXO GROUP LIMITED (GB) 2005-10-12 EP disclosed
WO-2004087145-A2 ANTIBACTERIAL AGENTS GLAXO GROUP LIMITED (GB) 2004-10-14 WO disclosed
WO-2004002490-A2 PIPERIDINE COMPOUNDS AS ANTIBACTERIALS GLAXO GROUP LIMITED (GB) 2004-01-08 WO disclosed
US-5254560-A Treating disorders involving hyperactivity of adrenergic system in lower urinary tract SYNTHELABO (FR) 1993-10-19 US disclosed
US-5246939-A Antiadrenergic systems for lower urinary apparatus SYNTHELABO (FR) 1993-09-21 US disclosed
US-5244894-A Treating disorders involving hyperactivity of the alpha 1-adrenergic system in lower urinary tract SYNTHELABO 1993-09-14 US disclosed
US-4600758-A 5-SULFAMOYL-3-OXOISOINDOLES WITH ARLYPIPERIDINYL MOIETIES, DIURETICS, HYPOTENSIVES MEAD JOHNSON & COMPANY (US) 1986-07-15 US disclosed