Styrene

Styrene

SCHEMBL8531986

C=Cc1ccccc1.CC(=CC12CC3CC(CC(C3)C1)C2)C(=O)O

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.44
ALDH1A1 P00352 3/20 0.40
TSHR P16473 2/20 0.40
GABBR2 O75899 1/20 0.40
GABRB1 P18505 1/20 0.40
GABRB2 P47870 1/20 0.40
GABBR1 Q9UBS5 1/20 0.40
FAAH O00519 2/20 0.37
LMNA P02545 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
KDM1A O60341 1/20 0.36
P2RX7 Q99572 4/20 0.35
EPHX2 P34913 2/20 0.35
CNR2 P34972 2/20 0.35
HTT P42858 2/20 0.35
HPGD P15428 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
ALOX12 P18054 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL757168 0.83 THRB (0.39) ALDH1A1EPHX2HSD17B10
SCHEMBL157720 0.83 THRB (0.39) ALDH1A1EPHX2HSD17B10
SCHEMBL28531021 0.75 KDM4E (0.40) FAAHLMNAMEN1KMT2AP2RX7
Styrene SCHEMBL238869 0.74 AKR1C3 (0.59) AKR1C3ALDH1A1TSHRLMNAMEN1
Styrene SCHEMBL134355 0.74 AKR1C3 (0.59) AKR1C3ALDH1A1TSHRLMNAMEN1
SCHEMBL6536553 0.74 THRB (0.31)
SCHEMBL6536551 0.74 THRB (0.31)
SCHEMBL3680655 0.73 ALDH1A1 (0.35) ALDH1A1TSHRLMNAMEN1KMT2A
Styrene SCHEMBL1628243 0.73 AKR1C3 (0.81) AKR1C3ALDH1A1TSHRMEN1KMT2A
SCHEMBL3680657 0.73 ALDH1A1 (0.35) ALDH1A1TSHRLMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8975327-B2 Controlling morphology of block copolymers DOW CORNING CORPORATION (US) 2015-03-10 US disclosed
EP-2643413-A1 CONTROLLING MORPHOLOGY OF BLOCK COPOLYMERS Dow Corning Corporation (US) 2013-10-02 EP disclosed
US-20130231438-A1 Controlling Morphology of Block Copolymers DOW CORNING CORPORATION (US) 2013-09-05 US disclosed
WO-2012071330-A1 CONTROLLING MORPHOLOGY OF BLOCK COPOLYMERS DOW CORNING CORPORATION (US) 2012-05-31 WO disclosed