SCHEMBL8532164

SCHEMBL8532164

CCCCCCCC[C@@H](O)C(F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.45
SPHK1 Q9NYA1 2/20 0.45
FFAR1 O14842 2/20 0.45
LMNA P02545 2/20 0.44
MAPT P10636 2/20 0.43
CYP2D6 P10635 2/20 0.42
GMNN O75496 1/20 0.42
POLB P06746 1/20 0.42
THPO P40225 1/20 0.42
MTOR P42345 1/20 0.42
BLM P54132 1/20 0.42
KDM4E B2RXH2 1/20 0.42
TP53 P04637 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CETP P11597 1/20 0.42
HTT P42858 1/20 0.42
UBE2N P61088 1/20 0.42
FFAR4 Q5NUL3 1/20 0.41
FAAH O00519 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7794969 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL9173116 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL574572 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL9175499 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL9170033 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL8375750 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL9177080 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL9173507 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL1350818 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL9440703 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0579770-B1 MACROCYCLIC LACTAM PROKINETIC AGENTS ABBOTT LAB (US) 1996-06-26 EP claimed
US-5776365-A COMPOUNDS WITH OPTICAL ACTIVITY AND SWITCHES FOR CONTRAST MITSUI CHEMICALS, INC. (JP) 1998-07-07 US disclosed
US-5725798-A CARBOXYLIC ESTERS FOR ELECTRICAL APPARATUS, SWITCHES AND CONTRAST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-03-10 US disclosed
EP-0586263-B1 A liquid crystal compound SHOWA SHELL SEKIYU (JP) 1997-03-26 EP disclosed
EP-0571277-B1 Antiferroelectric liquid crystal compound SHOWA SHELL SEKIYU (JP) 1996-06-26 EP disclosed
EP-0439185-B1 Liquid crystal compound SHOWA SHELL SEKIYU (JP) 1995-11-22 EP disclosed
US-5433887-A Liquid crystal compounds SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1995-07-18 US disclosed
US-5417885-A Antiferroelectric liquid crystal compound SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1995-05-23 US disclosed
EP-0422996-B1 Liquid crystal compound SHOWA SHELL SEKIYU (JP) 1995-04-12 EP disclosed
EP-0637624-A1 Antiferroelectric liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1995-02-08 EP disclosed
EP-0586263-A1 A liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1994-03-09 EP disclosed
EP-0571277-A1 Antiferroelectric liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1993-11-24 EP disclosed
US-5262086-A Used as photoelectric element utilizing response to an electric field; exhibits high optical purity SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1993-11-16 US disclosed
US-5207947-A Trifluoroalkyl diaryl triesters; antiferroelectricity; electrooptics SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1993-05-04 US disclosed
US-5202054-A Exhibits three stable states of molecular orientation useful in displaying and electrooptics SHOWA SHELL SEKIYU K.K. (JP) 1993-04-13 US disclosed
US-5171471-A Having wide range of phase transition temperatures for faster optical response times SHOWA SHELL SEKIYU K.K. (JP) 1992-12-15 US disclosed
EP-0439185-A2 Liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1991-07-31 EP disclosed
EP-0430205-A2 Liquid cristal display device MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-06-05 EP disclosed
EP-0422996-A2 Liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1991-04-17 EP disclosed
EP-0332392-A2 Dioxane liquid crystal compounds Showa Shell Sekiyu Kabushiki Kaisha (JP) 1989-09-13 EP disclosed