SCHEMBL1350818

SCHEMBL1350818

CCCCCC[C@@H](O)C(F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.45
SPHK1 Q9NYA1 2/20 0.45
FFAR1 O14842 2/20 0.45
LMNA P02545 2/20 0.44
MAPT P10636 2/20 0.43
CYP2D6 P10635 2/20 0.42
GMNN O75496 1/20 0.42
POLB P06746 1/20 0.42
THPO P40225 1/20 0.42
MTOR P42345 1/20 0.42
BLM P54132 1/20 0.42
KDM4E B2RXH2 1/20 0.42
TP53 P04637 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CETP P11597 1/20 0.42
HTT P42858 1/20 0.42
UBE2N P61088 1/20 0.42
FFAR4 Q5NUL3 1/20 0.41
FAAH O00519 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7794969 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL9173116 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL574572 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL9175499 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL8532164 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL9170033 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL8375750 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL9177080 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL9173507 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNAMAPT
SCHEMBL9440703 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5255196-A None JP disclosed
JP-6025098-A None JP disclosed
JP-4117343-A None JP disclosed
CN-102289096-B Liquid crystal display element with fast response and continuous gray scale UNIV HONG KONG SCIENCE & TECHN 2015-01-21 CN disclosed
US-8755022-B2 Liquid crystal display cell with fast response and continuous gray scale THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2014-06-17 US disclosed
US-20110285928-A1 Liquid crystal display cell with fast response and continuous gray scale THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2011-11-24 US disclosed
US-7083832-B2 Partially fluorinated liquid crystal material DISPLAYTECH, INC. (US) 2006-08-01 US disclosed
EP-0884309-B1 Optically active compound, antiferroelectric liquid crystal composition containing the same, process for producing the same and process for producing optically active carboxylic acid SEMICONDUCTOR ENERGY LAB (JP) 2005-09-07 EP disclosed
US-6703082-B1 VARIOUS NAPHTHALENE-CONTAINING LIQUID CRYSTALS DISPLAYTECH, INC. 2004-03-09 US disclosed
US-20030017278-A1 Partially fluorinated liquid crystal material CITIZEN FINETECH MIYOTA CO., LTD. (JP) 2003-01-23 US disclosed
EP-0474196-A1 Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1992-03-11 EP disclosed
EP-0465048-A2 Carboxylic acid ester compound, liquid crystal compound, liquid crystal composition, liquid crystal element and light modulation method MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-01-08 EP disclosed
EP-0439185-A2 Liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1991-07-31 EP disclosed
EP-0439190-A2 Component for liquid crystal composition and liquid crystal composition containing the same Showa Shell Sekiyu Kabushiki Kaisha (JP) 1991-07-31 EP disclosed
EP-0422996-A2 Liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1991-04-17 EP disclosed
EP-0413585-A1 Carboxylate compounds, liquid crystal compositions containing said compounds and liquid crystal element MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-02-20 EP disclosed
EP-0409634-A2 Liquid crystal compounds and optically active compounds SANYO CHEMICAL INDUSTRIES LTD. (JP) 1991-01-23 EP disclosed
EP-0401961-A2 Carboxylic acid esters and their use in liquid crystal compositions MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-12-12 EP disclosed
EP-0355772-A2 Liquid-crystalline copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-02-28 EP disclosed
EP-0341922-A2 Naphthalene compound and liquid crystal composition containing the same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-11-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030017278-A1 Partially fluorinated liquid crystal material LEF1, SETDB1, INF2 GPR84 3787/4885SPHK1 1345/4885FFAR1 958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.