⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20115478 | 0.77 | — | — | |
| SCHEMBL25846538 | 0.77 | — | — | |
| SCHEMBL14252171 | 0.77 | — | — | |
| SCHEMBL25840174 | 0.77 | — | — | |
| SCHEMBL810589 | 0.74 | — | — | |
| SCHEMBL16786186 | 0.72 | — | — | |
| SCHEMBL16786189 | 0.72 | — | — | |
| SCHEMBL123544 | 0.71 | — | — | |
| SCHEMBL5605853 | 0.70 | ALDH1A1 (0.30) | — | |
| SCHEMBL29131250 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792756-A | PHOSPHONATE NUCLEOTIDE ANALOG ANTIVIRAL/ANTITUMOR AGENT FOR ORAL DRUG DELIVERY | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1998-08-11 | — | — | US | disclosed |
| EP-0481214-B1 | Prodrugs of phosphonates | ACAD OF SCIENCE CZECH REPUBLIC (CZ) | 1998-06-24 | — | — | EP | disclosed |
| US-5663159-A | VIRICIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1997-09-02 | — | — | US | disclosed |
| EP-0481214-A1 | Prodrugs of phosphonates | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1992-04-22 | — | — | EP | disclosed |