⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30495540 | 0.80 | CES2 (0.32) | — | |
| SCHEMBL123544 | 0.79 | — | — | |
| SCHEMBL6595028 | 0.79 | — | — | |
| SCHEMBL8159098 | 0.79 | PKM (0.30) | — | |
| SCHEMBL20115478 | 0.79 | — | — | |
| SCHEMBL8532244 | 0.77 | — | — | |
| SCHEMBL669549 | 0.77 | — | — | |
| SCHEMBL8532247 | 0.74 | — | — | |
| SCHEMBL770602 | 0.74 | — | — | |
| SCHEMBL16786189 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10689522-B2 | Fluorine compounds | MERCK PATENT GMBH (DE) | 2020-06-23 | — | — | US | disclosed |
| EP-2399895-B1 | Process for producing optically active aliphatic fluoroalcohol | KANTO KAGAKU (JP) | 2018-08-08 | — | — | EP | disclosed |
| US-20170349761-A1 | FLUORINE COMPOUNDS | MERCK PATENT GMBH (DE) | 2017-12-07 | — | — | US | disclosed |
| US-8558033-B2 | Process for producing optically active aliphatic fluoroalcohol | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2013-10-15 | — | — | US | disclosed |
| US-20110319671-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALIPHATIC FLUOROALCOHOL | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2011-12-29 | — | — | US | disclosed |
| EP-2399895-A2 | Process for producing optically active aliphatic fluoroalcohol | Kanto Kagaku Kabushiki Kaisha (JP) | 2011-12-28 | — | — | EP | disclosed |