Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 1.00 |
| ▸ | MMP9 | P14780 | 2/20 | 1.00 |
| ▸ | MMP8 | P22894 | 2/20 | 1.00 |
| ▸ | MMP13 | P45452 | 2/20 | 1.00 |
| ▸ | MMP2 | P08253 | 1/20 | 1.00 |
| ▸ | ILK | Q13418 | 1/20 | 0.64 |
| ▸ | MGAM | O43451 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4224543 | 0.93 | APP (0.86) | APPMMP9MMP8MMP13MMP2 | |
| SCHEMBL27909857 | 0.92 | APP (0.84) | APPMMP9MMP8MMP13MMP2 | |
| SCHEMBL8433475 | 0.86 | APP (0.76) | APPMMP9MMP8MMP13MMP2 | |
| SCHEMBL1996999 | 0.84 | APP (0.73) | APPMMP9MMP8MMP13MMP2 | |
| SCHEMBL2628260 | 0.84 | APP (0.73) | APPMMP9MMP8MMP13MMP2 | |
| SCHEMBL5326815 | 0.84 | MMP13 (0.74) | APPMMP9MMP8MMP13MMP2 | |
| SCHEMBL8396940 | 0.84 | APP (0.72) | APPMMP9MMP8MMP13MMP2 | |
| SCHEMBL29474819 | 0.83 | RAB9A (0.81) | APPMMP9MMP8MMP13MMP2 | |
| SCHEMBL366824 | 0.83 | RAB9A (0.81) | APPMMP9MMP8MMP13MMP2 | |
| SCHEMBL28723346 | 0.82 | MMP13 (0.68) | APPMMP9MMP8MMP13MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118725333-A | Keggin type polyacid-based metal organic framework molecular material, synthesis method and application of Keggin type polyacid-based metal organic framework molecular material as photocatalyst | 周口师范学院 | 2024-10-01 | — | — | CN | claimed |
| CN-102942537-B | Benzothiazole-aniline compound used as pH fluorescent probe and preparation method thereof | UNIV ZHEJIANG | 2014-07-02 | — | — | CN | claimed |
| CN-102942537-A | Benzothiazole-aniline compound used as pH fluorescent probe and preparation method thereof | UNIV ZHEJIANG | 2013-02-27 | — | — | CN | claimed |
| CN-118725333-A | Keggin type polyacid-based metal organic framework molecular material, synthesis method and application of Keggin type polyacid-based metal organic framework molecular material as photocatalyst | 周口师范学院 | 2024-10-01 | — | — | CN | disclosed |
| CN-117777327-A | Manganese-based catalyst, preparation method and application | 铜仁学院 | 2024-03-29 | — | — | CN | disclosed |
| CN-115197165-B | Method for preparing benzothiazole compound by reacting photocatalytic toluene compound and o-aminophenylsulfiol | 河南师范大学 | 2024-01-26 | — | — | CN | disclosed |
| US-20230296820-A1 | POLARIZING PLATE AND IMAGE DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2023-09-21 | — | — | US | disclosed |
| US-11732191-B2 | Compound, polymerizable composition, cured product, optical film, polarizing plate, and image display device | FUJIFILM CORPORATION (JP) | 2023-08-22 | — | — | US | disclosed |
| CN-115057830-B | Method for synthesizing 2-aryl benzothiazole | 辽宁科技大学 | 2023-08-18 | — | — | CN | disclosed |
| US-20230228928-A1 | OPTICAL LAMINATE, POLARIZING PLATE, AND IMAGE DEVICE DISPLAY | FUJIFILM CORPORATION (JP) | 2023-07-20 | — | — | US | disclosed |
| US-20230143665-A1 | FLUORINE-CONTAINING POLYMER, COMPOSITION, OPTICAL FILM, LIQUID CRYSTAL FILM, HARDCOAT FILM, AND POLARIZING PLATE | FUJIFILM CORPORATION (JP) | 2023-05-11 | — | — | US | disclosed |
| WO-2004064869-A2 | AMYLOID-BINDING, METAL-CHELATING AGENTS | THE GENERAL HOSPITAL CORPORATION (US) | 2004-08-05 | — | — | WO | disclosed |
| US-20030236391-A1 | Imaging amyloid deposits in living patients, with an amyloid binding agents having radiolabeled iodine; radiotherapy | UNIVERSITY OF PITTSBURGH | 2003-12-25 | — | — | US | disclosed |
| EP-1334091-A2 | THIOFLAVIN DERIVATIVES AND THEIR USE IN DIAGNOSIS AND THERAPY OF ALZHEIMER'S DISEASE | UNIVERSITY OF PITTSBURGH (US) | 2003-08-13 | — | — | EP | disclosed |
| US-20020133019-A1 | Thioflavin derivatives for use in antemortem diagnosis of alzheimer's disease and vivo imaging and prevention of amyloid deposition | PITTSBURGH, UNIVERSITY OF | 2002-09-19 | — | — | US | disclosed |
| WO-2002016333-A2 | THIOFLAVIN DERIVATIVES AND THEIR USE IN DIAGNOSIS AND THERAPHY OF ALZHEIMER'S DISEASE | UNIVERSITY OF PITTSBURGH (US) | 2002-02-28 | — | — | WO | disclosed |
| EP-0721336-B1 | BENZAZOLE COMPOUNDS FOR USE IN THERAPY | CANCER RES CAMPAIGN TECH (GB) | 1999-07-14 | — | — | EP | disclosed |
| US-5874431-A | ANTITUMOR AGENTS; BREAST CANCER | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1999-02-23 | — | — | US | disclosed |
| EP-0721336-A1 | BENZAZOLE COMPOUNDS FOR USE IN THERAPY | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1996-07-17 | — | — | EP | disclosed |
| WO-1995006469-A1 | BENZAZOLE COMPOUNDS FOR USE IN THERAPY | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1995-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020133019-A1 | Thioflavin derivatives for use in antemortem diagnosis of alzheimer's disease and vivo imaging and prevention of amyloid deposition | APP, PSEN2, MAPT | APP 1/4885MMP9 4390/4885MMP8 4324/4885 |
| US-20030236391-A1 | Imaging amyloid deposits in living patients, with an amyloid binding agents having radiolabeled iodine; radiotherapy | TTR, APP, BACE1 | APP 2/4885MMP9 4786/4885MMP8 4614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.