Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | AGT | P01019 | 2/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541811 | 0.94 | AGTR1 (0.50) | AGTR1AGTR2AKT1AGTPDCD1 | |
| SCHEMBL489527 | 0.93 | AGTR1 (0.49) | AGTR1AGTR2AKT1AGTPDCD1 | |
| SCHEMBL3950208 | 0.92 | AGTR1 (0.49) | AGTR1AGTR2AGTPDCD1CD274 | |
| SCHEMBL9093218 | 0.90 | AGTR1 (0.48) | AGTR1AGTR2AKT1AGTPDCD1 | |
| SCHEMBL13146764 | 0.85 | AGTR1 (0.55) | AGTR1AGTR2AGT | |
| SCHEMBL4554761 | 0.83 | AGTR1 (0.44) | AGTR1AGTR2AGTPDCD1CD274 | |
| SCHEMBL839523 | 0.82 | CD274 (0.51) | AGTR1AGTR2AKT1AGTPDCD1 | |
| SCHEMBL839981 | 0.81 | AGTR1 (0.47) | AGTR1AGTR2AGTPDCD1CD274 | |
| SCHEMBL839982 | 0.81 | AGTR1 (0.47) | AGTR1AGTR2AGTPDCD1CD274 | |
| SCHEMBL9024777 | 0.81 | AGTR1 (0.51) | AGTR1AGTR2AKT1AGT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846991-A | Pyrazole derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-08 | — | — | US | disclosed |
| WO-1993017682-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1993-09-16 | — | — | WO | disclosed |
| WO-1993018035-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1993-09-16 | — | — | WO | disclosed |