Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | AGT | P01019 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4246354 | 0.87 | AGTR1 (0.50) | AGTR1AGTR2AGT | |
| SCHEMBL8907583 | 0.84 | AGTR1 (0.51) | AGTR1AGTR2AGTHSD11B1 | |
| SCHEMBL30316147 | 0.83 | AGTR1 (0.51) | AGTR1AGTR2AGT | |
| SCHEMBL9024777 | 0.83 | AGTR1 (0.51) | AGTR1AGTR2AGT | |
| SCHEMBL796 | 0.82 | AGTR1 (0.50) | AGTR1AGTR2AGT | |
| SCHEMBL29404889 | 0.82 | AGTR1 (0.50) | AGTR1AGTR2AGT | |
| SCHEMBL8246839 | 0.82 | AGTR1 (0.50) | AGTR1AGTR2AGT | |
| SCHEMBL8539585 | 0.82 | AGTR1 (0.52) | AGTR1AGTR2AGT | |
| SCHEMBL13146764 | 0.82 | AGTR1 (0.55) | AGTR1AGTR2AGTHSD11B1 | |
| SCHEMBL9307853 | 0.82 | AGTR1 (0.50) | AGTR1AGTR2AGT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846991-A | Pyrazole derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-08 | — | — | US | disclosed |