Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3690365 | 0.89 | MAPT (0.59) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1901172 | 0.89 | ALDH1A1 (0.76) | ALDH1A1HSD17B10CYP1A2RAB9APOLB | |
| SCHEMBL29654057 | 0.85 | ALDH1A1 (0.62) | ALDH1A1HSD17B10CYP1A2RAB9APOLB | |
| SCHEMBL5459330 | 0.85 | ALDH1A1 (0.62) | ALDH1A1HSD17B10CYP1A2RAB9APOLB | |
| SCHEMBL1303329 | 0.84 | ALDH1A1 (0.72) | ALDH1A1HSD17B10CYP1A2RAB9APOLB | |
| SCHEMBL8350546 | 0.84 | GAA (0.50) | ALDH1A1HSD17B10CYP1A2RAB9APOLB | |
| SCHEMBL11925383 | 0.83 | SMN1; SMN2 (0.67) | ALDH1A1HSD17B10RAB9APOLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL695094 | 0.82 | ALDH1A1 (0.70) | ALDH1A1HSD17B10CYP1A2RAB9APOLB | |
| SCHEMBL4795890 | 0.82 | KMT2A (0.66) | ALDH1A1CYP1A2RAB9APOLBMAPT | |
| SCHEMBL17933240 | 0.82 | MEN1 (0.57) | ALDH1A1CYP1A2RAB9APOLBNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696110-A | ANTIULCER AGENTS | MERCK, SHARP & DOHME, LTD. (GB) | 1997-12-09 | — | — | US | claimed |
| US-20200369901-A1 | DISPERSION, INK JET RECORDING METHOD, RECORDED MATERIAL, AND COMPOUND | FUJIFILM CORPORATION (JP) | 2020-11-26 | — | — | US | disclosed |
| CN-1043344-C | New heterocyclic compounds | KRONSEDER MASCHF KRONES (JP) | 1999-05-12 | — | — | CN | disclosed |
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| US-5696110-A | ANTIULCER AGENTS | MERCK, SHARP & DOHME, LTD. (GB) | 1997-12-09 | — | — | US | disclosed |