Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 4/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.39 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24136540 | 0.86 | NMT1 (0.48) | NMT1F2PLGAVPR1AAVPR1B | |
| SCHEMBL13663687 | 0.84 | NMT1 (0.49) | NMT1F2PLGAVPR1AAVPR1B | |
| SCHEMBL20781368 | 0.84 | NMT1 (0.49) | NMT1F2PLGAVPR1AAVPR1B | |
| SCHEMBL6432992 | 0.83 | NMT1 (0.48) | NMT1F2PLGAVPR1AAVPR1B | |
| SCHEMBL13662187 | 0.81 | F2 (0.47) | NMT1F2PLGAVPR1AAVPR1B | |
| SCHEMBL24476908 | 0.79 | NMT1 (0.44) | NMT1F2PLGAVPR1AAVPR1B | |
| SCHEMBL2372022 | 0.78 | NMT1 (0.57) | NMT1F2AVPR1AAVPR1BNR3C1 | |
| SCHEMBL2372018 | 0.76 | NMT1 (0.56) | NMT1F2PLGAVPR1AAVPR1B | |
| SCHEMBL19147239 | 0.76 | NMT1 (0.54) | NMT1F2PLGAVPR1AAVPR1B | |
| SCHEMBL10526657 | 0.74 | NMT1 (0.49) | NMT1F2AVPR1AAVPR1BNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5831001-A | ADMINISTERING OLIGOPEPTIDE WITH ARGININE UNITS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1998-11-03 | — | — | US | disclosed |
| US-5789531-A | Peptide-based inhibitors of HIV replication | ALLEX BIOPHARMACEUTICALS, INC. (CA) | 1998-08-04 | — | — | US | disclosed |
| US-5646120-A | OLIGO- AND POLYARGININE AND DERIVATIVES | ALLELIX BIOPHARMACEUTICALS, INC. (CA) | 1997-07-08 | — | — | US | disclosed |