SCHEMBL2372018

SCHEMBL2372018

[CH2]NS(=O)(=O)c1c(C)cc(OC)c(C)c1C

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NMT1 P30419 2/20 0.56
F2 P00734 2/20 0.46
AVPR1B P47901 4/20 0.40
AVPR1A P37288 5/20 0.39
NR3C1 P04150 1/20 0.39
PGR P06401 1/20 0.39
NR3C2 P08235 1/20 0.39
EPHX2 P34913 1/20 0.37
PKM P14618 1/20 0.37
ALPL P05186 1/20 0.37
ALDH1A1 P00352 1/20 0.36
PLG P00747 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2372022 0.84 NMT1 (0.57) NMT1F2AVPR1BAVPR1ANR3C1
SCHEMBL27544457 0.80 NMT1 (0.51) NMT1F2AVPR1BAVPR1ANR3C1
SCHEMBL16502964 0.79 NMT1 (0.63) NMT1F2NR3C1PGRNR3C2
SCHEMBL19147239 0.79 NMT1 (0.54) NMT1F2AVPR1BAVPR1ANR3C1
SCHEMBL8295856 0.78 NMT1 (0.50) NMT1F2AVPR1BNR3C1PGR
SCHEMBL248149 0.78 NMT1 (0.50) NMT1F2AVPR1BAVPR1ANR3C1
SCHEMBL13940302 0.78 NMT1 (0.51) NMT1F2AVPR1BAVPR1ANR3C1
SCHEMBL10526657 0.77 NMT1 (0.49) NMT1F2AVPR1BAVPR1ANR3C1
SCHEMBL3449519 0.77 NMT1 (0.49) NMT1F2AVPR1BAVPR1ANR3C1
SCHEMBL29381119 0.77 NMT1 (0.49) NMT1F2NR3C1PGRNR3C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2547204-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS Bayer Intellectual Property GmbH (DE) 2013-01-23 EP claimed
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 US claimed
WO-2011113861-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 WO claimed
EP-2547204-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS Bayer Intellectual Property GmbH (DE) 2013-01-23 EP disclosed
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 US disclosed
WO-2011113861-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS STS, ARSA, TST NMT1 1282/4885F2 4287/4885AVPR1B 3219/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.