Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.38 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2372022 | 0.80 | NMT1 (0.57) | NMT1F2AVPR1AAVPR1BNR3C1 | |
| SCHEMBL2372018 | 0.79 | NMT1 (0.56) | NMT1F2AVPR1AAVPR1BNR3C1 | |
| SCHEMBL3449519 | 0.76 | NMT1 (0.49) | NMT1F2AVPR1AAVPR1BNR3C1 | |
| SCHEMBL8533140 | 0.76 | NMT1 (0.50) | NMT1F2AVPR1AAVPR1BNR3C1 | |
| SCHEMBL27544457 | 0.76 | NMT1 (0.51) | NMT1F2AVPR1AAVPR1BNR3C1 | |
| SCHEMBL16502964 | 0.75 | NMT1 (0.63) | NMT1F2NR3C1PGRNR3C2 | |
| SCHEMBL20781368 | 0.75 | NMT1 (0.49) | NMT1F2AVPR1AAVPR1BNR3C1 | |
| SCHEMBL13663687 | 0.75 | NMT1 (0.49) | NMT1F2AVPR1AAVPR1BNR3C1 | |
| SCHEMBL8295856 | 0.74 | NMT1 (0.50) | NMT1F2AVPR1BNR3C1PGR | |
| SCHEMBL248149 | 0.74 | NMT1 (0.50) | NMT1F2AVPR1AAVPR1BNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017122722-A1 | BIHETEROCYCLIC COMPOUND | 大日本住友製薬株式会社 | 2017-07-20 | — | — | WO | disclosed |