Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CAD | P27708 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11407299 | 0.85 | L3MBTL1 (0.61) | L3MBTL1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL8176274 | 0.84 | L3MBTL1 (0.42) | L3MBTL1KMT2APOLBALDH1A1HSD17B10 | |
| SCHEMBL6006458 | 0.81 | CA1 (0.42) | L3MBTL1KMT2APOLBGAAMGAM | |
| SCHEMBL19091365 | 0.81 | L3MBTL1 (0.65) | L3MBTL1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL13108405 | 0.80 | L3MBTL1 (0.69) | L3MBTL1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL13099456 | 0.80 | L3MBTL1 (0.69) | L3MBTL1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL3565347 | 0.80 | L3MBTL1 (0.69) | L3MBTL1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL8176228 | 0.80 | CAD (0.41) | L3MBTL1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL20988252 | 0.79 | L3MBTL1 (0.63) | L3MBTL1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL21221231 | 0.79 | L3MBTL1 (0.67) | L3MBTL1KMT2APOLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996004254-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |