Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9293943 | 1.00 | TRPV1 (0.51) | TRPV1MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL8533704 | 0.93 | TRPV1 (0.54) | TRPV1MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL8427410 | 0.87 | TRPV1 (0.46) | TRPV1MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL8532835 | 0.85 | — | — | |
| SCHEMBL159361 | 0.85 | — | — | |
| SCHEMBL8427434 | 0.84 | TRPV1 (0.45) | TRPV1MEN1KMT2A | |
| SCHEMBL8536466 | 0.83 | CA12 (0.47) | TRPV1MTNR1AMTNR1B | |
| SCHEMBL9669803 | 0.83 | KMT2A (0.46) | TRPV1MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL8533902 | 0.80 | GPR84 (0.46) | TRPV1MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL8533040 | 0.80 | GPR84 (0.46) | TRPV1MTNR1AMTNR1BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432984-B1 | Carbamoyl derivatives | ZENECA LTD (GB) | 1998-03-04 | — | — | EP | claimed |
| US-5286740-A | Leukotrine antagonists; antiinflammatory agnets, antiallergens, treating asthma | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-02-15 | — | — | US | claimed |
| EP-0432984-A2 | Carbamoyl derivatives | ZENECA LIMITED (GB) | 1991-06-19 | — | — | EP | claimed |
| JP-7070061-A | — | — | None | — | — | JP | disclosed |
| EP-0432984-B1 | Carbamoyl derivatives | ZENECA LTD (GB) | 1998-03-04 | — | — | EP | disclosed |
| JP-H0770061-A | CARBAMOYL DERIVATIVE | ZENECA LTD | 1995-03-14 | — | — | JP | disclosed |
| US-5334765-A | Intermediate for leukotriene antagonists | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-08-02 | — | — | US | disclosed |
| US-5286740-A | Leukotrine antagonists; antiinflammatory agnets, antiallergens, treating asthma | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-02-15 | — | — | US | disclosed |
| EP-0432984-A2 | Carbamoyl derivatives | ZENECA LIMITED (GB) | 1991-06-19 | — | — | EP | disclosed |