Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | STK17B | O94768 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL877529 | 0.75 | ADORA3 (0.33) | CYP19A1KDM4EHSD17B10MAOBADORA3 | |
| SCHEMBL15287877 | 0.72 | ADORA3 (0.36) | CYP19A1KDM4EHSD17B10MAOBADORA3 | |
| SCHEMBL19450713 | 0.66 | CYP19A1 (0.47) | CYP19A1KDM4EHSD17B10MAOBADORA3 | |
| SCHEMBL19456823 | 0.66 | CYP19A1 (0.47) | CYP19A1KDM4EHSD17B10MAOBADORA3 | |
| SCHEMBL1429502 | 0.64 | STK17B (0.46) | CYP19A1KDM4EHSD17B10MAOBADORA3 | |
| SCHEMBL31015940 | 0.62 | RET (0.41) | CYP19A1KDM4EHSD17B10MAOBADORA3 | |
| SCHEMBL9932454 | 0.62 | PBRM1 (0.40) | CYP19A1ARMEN1KMT2A | |
| SCHEMBL891447 | 0.62 | PBRM1 (0.40) | CYP19A1ARMEN1KMT2A | |
| SCHEMBL882871 | 0.62 | PBRM1 (0.40) | CYP19A1ARMEN1KMT2A | |
| SCHEMBL8515749 | 0.60 | CYP19A1 (0.40) | CYP19A1KDM4EHSD17B10MAOBADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012071458-A1 | HETEROCYCLIC INHIBITORS OF BETA - SECRETASE FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2012-05-31 | — | — | WO | disclosed |