Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FABP7 | O15540 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5842444 | 0.71 | GRM2 (0.52) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL5841333 | 0.69 | GRM8 (0.44) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL1956495 | 0.69 | HPGD (0.44) | ALDH1A1POLBGAA | |
| SCHEMBL7124212 | 0.69 | SLC1A2 (0.50) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL4810978 | 0.69 | SLC1A2 (0.50) | GRM8GRM6GRM2GRM3SLC1A2 | |
| Hydrochloric Acid SCHEMBL4810967 | 0.68 | SLC1A2 (0.49) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL10418525 | 0.67 | RAB9A (0.40) | ALDH1A1POLBGAA | |
| SCHEMBL6697973 | 0.66 | GRM2 (0.67) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL5690924 | 0.66 | SLC1A2 (0.46) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL1615863 | 0.65 | L3MBTL1 (0.45) | ALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696577-B1 | Synthetic excitatory amino acids | LILLY CO ELI (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1996005175-A1 | SYNTHETIC EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 1996-02-22 | — | — | WO | disclosed |
| EP-0696577-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |