Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | HTR2B | P41595 | 4/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | HRH2 | P25021 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15535434 | 0.82 | KDM4E (0.40) | HTR2CHTR2BADRB2HTR1ACHRM5 | |
| SCHEMBL29164221 | 0.81 | MAPT (0.40) | HTR2CHTR2BADRB2HTR1ACHRM5 | |
| SCHEMBL28338065 | 0.80 | CYP3A4 (0.40) | TDP1ALDH1A1RAB9AKMT2ANPC1 | |
| SCHEMBL3248506 | 0.79 | MAPT (0.44) | ATMTDP1ALDH1A1HIF1AHSPB1 | |
| SCHEMBL2653971 | 0.77 | ATM (0.49) | ADRA2AADRA2BADRA2CATMTDP1 | |
| SCHEMBL6445803 | 0.77 | L3MBTL1 (0.49) | HTR2CHTR2AATMTDP1ALDH1A1 | |
| SCHEMBL1978052 | 0.77 | S1PR4 (0.52) | HTR1ATDP1ALDH1A1HIF1AHSPB1 | |
| SCHEMBL3884042 | 0.77 | ALDH1A1 (0.49) | HTR2CHTR2AATMTDP1ALDH1A1 | |
| SCHEMBL1680978 | 0.77 | HTR2C (0.39) | HTR2CHTR2BADRB2HTR1ACHRM5 | |
| SCHEMBL10718874 | 0.76 | ATM (0.40) | ATMTDP1ALDH1A1HIF1AHSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786301-A | HERBICIDES | ZENECA LIMITED (GB) | 1998-07-28 | — | — | US | disclosed |
| EP-0696278-B1 | HERBICIDAL SUBSTITUTED 1-PHENYL OR 1-PYRIDINYL-BENZOTRIAZOLES | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |
| CN-1124959-A | Herbicidal substituted 1-phenyl or 1-pyridyl benzotriazoles | ZENECA LTD (GB) | 1996-06-19 | — | — | CN | disclosed |
| EP-0696278-A1 | HERBICIDAL SUBSTITUTED 1-PHENYL OR 1-PYRIDINYL-BENZOTRIAZOLES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| US-5369086-A | Herbicides | ZENECA LIMITED (GB) | 1994-11-29 | — | — | US | disclosed |
| WO-1994025446-A1 | HERBICIDAL SUBSTITUTED 1-PHENYL OR 1-PYRIDINYL-BENZOTRIAZOLES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |