Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684645 | 0.83 | ALDH1A1 (0.55) | ALDH1A1KMT2ALMNAHTR1AL3MBTL1 | |
| SCHEMBL30373690 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KMT2ALMNAHTR1AL3MBTL1 | |
| SCHEMBL7345136 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KMT2ALMNAHTR1AL3MBTL1 | |
| SCHEMBL1599426 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KMT2ALMNAHTR1AL3MBTL1 | |
| SCHEMBL20906645 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KMT2ALMNAHTR1AL3MBTL1 | |
| SCHEMBL6640390 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KMT2ALMNAHTR1AL3MBTL1 | |
| SCHEMBL20906565 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KMT2ALMNAHTR1AL3MBTL1 | |
| SCHEMBL20906600 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KMT2ALMNAHTR1AL3MBTL1 | |
| SCHEMBL20906609 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KMT2ALMNAHTR1AL3MBTL1 | |
| SCHEMBL4502485 | 0.77 | HTR2A (0.53) | ALDH1A1KMT2ALMNAHTR1AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736523-A | ADMINISTERING TO THE MAMMAL SUFFERING FROM CANCER | BIOCHEM PHARMA INC. (CA) | 1998-04-07 | — | — | US | disclosed |
| US-5606037-A | Processes antineoplastic heteronaphthoquinones | BIOCHEM PHARMA INC. (CA) | 1997-02-25 | — | — | US | disclosed |
| EP-0659190-A1 | ANTINEOPLASTIC HETERONAPHTHOQUINONES | BIOCHEM PHARMA INC (CA) | 1995-06-28 | — | — | EP | disclosed |
| WO-1994011382-A1 | ANTINEOPLASTIC HETERONAPHTHOQUINONES | BIOCHEM PHARMA INC. (CA) | 1994-05-26 | — | — | WO | disclosed |