Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533328 | 0.83 | ALDH1A1 (0.58) | ALDH1A1KMT2ALMNAL3MBTL1GAA | |
| SCHEMBL1599426 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KMT2ALMNAL3MBTL1GAA | |
| SCHEMBL7396662 | 0.79 | L3MBTL1 (0.63) | ALDH1A1KMT2ALMNAL3MBTL1GAA | |
| SCHEMBL20921292 | 0.79 | L3MBTL1 (0.63) | ALDH1A1KMT2ALMNAL3MBTL1GAA | |
| SCHEMBL7399518 | 0.78 | ALDH1A1 (0.56) | ALDH1A1KMT2ALMNAL3MBTL1GAA | |
| SCHEMBL9683578 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KMT2ALMNAL3MBTL1GAA | |
| SCHEMBL7345136 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KMT2ALMNAL3MBTL1GAA | |
| SCHEMBL13197463 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KMT2ALMNAL3MBTL1GAA | |
| SCHEMBL4502485 | 0.77 | HTR2A (0.53) | ALDH1A1KMT2ALMNAL3MBTL1GAA | |
| SCHEMBL30373690 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KMT2ALMNAL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128369-A | Antiallergens, bronchodilator agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0404197-A2 | Arylalkylamine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-12-27 | — | — | EP | disclosed |