SCHEMBL8533479

SCHEMBL8533479

O=C(Cl)c1ccc2c(c1)S(=O)(=O)OC2=O

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.39
KMT2A Q03164 4/20 0.38
MEN1 O00255 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 6/20 0.33
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HPGD P15428 1/20 0.33
TTR P02766 1/20 0.32
LMNA P02545 1/20 0.32
PTPRC P08575 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8407445 0.85 CHEK1 (0.54) CHEK1KMT2AMEN1L3MBTL1ALDH1A1
SCHEMBL14199817 0.74 CHEK1 (0.61) CHEK1KMT2AMEN1L3MBTL1ALDH1A1
SCHEMBL12922991 0.72 CA12 (0.49) KMT2AMEN1L3MBTL1ALDH1A1TSHR
SCHEMBL11545963 0.72 ELANE (0.42) ALDH1A1
SCHEMBL12403806 0.71 TTR (0.47) CHEK1KMT2AMEN1L3MBTL1ALDH1A1
SCHEMBL3386406 0.71 CHEK1 (0.75) CHEK1KMT2AMEN1L3MBTL1ALDH1A1
SCHEMBL74379 0.69 CA12 (0.49) KMT2AALDH1A1TSHRTTRPTPRC
SCHEMBL29490657 0.69 CA12 (0.49) KMT2AALDH1A1TSHRTTRPTPRC
SCHEMBL12232345 0.69
SCHEMBL10623448 0.69 CHEK1 (0.59) CHEK1KMT2AMEN1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0517203-B1 Acid-dye resistant polyamide products and process for preparation BASF CORP (US) 1998-02-04 EP claimed
US-5562871-A CHEMICALLY BLOCKING A PORTION OF AMINO END GROUPS IN SULPHONATED POLYMER BASF CORPORATION (US) 1996-10-08 US claimed
US-5560973-A SULFONATED POLYMER BASF CORPORATION (US) 1996-10-01 US claimed
US-5548037-A INCLUDING SULFONATED GROUPS AND AN AMINE END BLOCKER BASF CORPORATION (US) 1996-08-20 US claimed
US-5545363-A SULFONATING, PIGMENTING, BLOCKING SULFONATED POLYAMIDE, FINALLY MELT SPINNING BASF CORPORATION (US) 1996-08-13 US claimed
US-5340886-A Acylation with a sulfonate compound, coloring, blocking and amidation with an alkyl anhydride, alkylaryl anhydride or a lactones BASF CORPORATION (US) 1994-08-23 US claimed
EP-0517203-A2 Acid-dye resistant polyamide products and process for preparation BASF CORPORATION (US) 1992-12-09 EP claimed
EP-0517203-B1 Acid-dye resistant polyamide products and process for preparation BASF CORP (US) 1998-02-04 EP disclosed
US-5562871-A CHEMICALLY BLOCKING A PORTION OF AMINO END GROUPS IN SULPHONATED POLYMER BASF CORPORATION (US) 1996-10-08 US disclosed
US-5560973-A SULFONATED POLYMER BASF CORPORATION (US) 1996-10-01 US disclosed
US-5548037-A INCLUDING SULFONATED GROUPS AND AN AMINE END BLOCKER BASF CORPORATION (US) 1996-08-20 US disclosed
US-5545363-A SULFONATING, PIGMENTING, BLOCKING SULFONATED POLYAMIDE, FINALLY MELT SPINNING BASF CORPORATION (US) 1996-08-13 US disclosed
US-5340886-A Acylation with a sulfonate compound, coloring, blocking and amidation with an alkyl anhydride, alkylaryl anhydride or a lactones BASF CORPORATION (US) 1994-08-23 US disclosed
EP-0517203-A2 Acid-dye resistant polyamide products and process for preparation BASF CORPORATION (US) 1992-12-09 EP disclosed
US-3996202-A Process for the preparation of sulfonate group containing aromatic polyamides HOECHST AKTIENGESELLSCHAFT (DT) 1976-12-07 US disclosed
US-3996202-A Process for the preparation of sulfonate group containing aromatic polyamides HOECHST AKTIENGESELLSCHAFT (DT) 1976-12-07 US disclosed