Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.54 |
| ▸ | TTR | P02766 | 3/20 | 0.47 |
| ▸ | PTPRC | P08575 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12403806 | 0.86 | TTR (0.47) | CHEK1TTRPTPRCKMT2APOLB | |
| SCHEMBL8533479 | 0.85 | CHEK1 (0.39) | CHEK1TTRPTPRCKMT2AMEN1 | |
| SCHEMBL2706112 | 0.74 | CHEK1 (0.69) | CHEK1TTRPTPRCKMT2APOLB | |
| SCHEMBL29789038 | 0.74 | CHEK1 (0.69) | CHEK1TTRPTPRCKMT2APOLB | |
| SCHEMBL14199812 | 0.73 | CHEK1 (0.84) | CHEK1TTRPTPRCKMT2AMEN1 | |
| SCHEMBL576238 | 0.73 | CA2 (0.39) | CA12CA2CA4CA7CA9 | |
| SCHEMBL31365268 | 0.71 | CHEK1 (0.65) | CHEK1TTRPTPRCKMT2APOLB | |
| SCHEMBL3399246 | 0.70 | CA12 (0.59) | CHEK1KMT2ACA12CA2CA4 | |
| SCHEMBL29643009 | 0.70 | CA12 (0.59) | CHEK1KMT2ACA12CA2CA4 | |
| SCHEMBL11547694 | 0.70 | CHEK1 (0.84) | CHEK1TTRPTPRCKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745336-B2 | Fluorescent dye compounds, conjugates and uses thereof | APPLIED BIOSYSTEMS, LLC (US) | 2017-08-29 | — | — | US | disclosed |
| US-20140303003-A1 | Fluorescent Dye Compounds, Conjugates and Uses Thereof | APPLIED BIOSYSTEMS, LLC (US) | 2014-10-09 | — | — | US | disclosed |
| US-7985602-B2 | Fluorescent dye compounds, conjugates and uses thereof | APPLIED BIOSYSTEMS, LLC (US) | 2011-07-26 | — | — | US | disclosed |
| US-7985602-B2 | Fluorescent dye compounds, conjugates and uses thereof | APPLIED BIOSYSTEMS, LLC (US) | 2011-07-26 | — | — | US | disclosed |
| US-20090093062-A1 | Fluorescent Dye Compounds, Conjugates and Uses Thereof | APPLERA CORPORATION (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090093062-A1 | Fluorescent Dye Compounds, Conjugates and Uses Thereof | APPLERA CORPORATION (US) | 2009-04-09 | — | — | US | disclosed |
| US-7256292-B2 | Fluorescent dye compounds, conjugates and uses thereof | APPLERA CORPORATION (US) | 2007-08-14 | — | — | US | disclosed |
| US-7256292-B2 | Fluorescent dye compounds, conjugates and uses thereof | APPLERA CORPORATION (US) | 2007-08-14 | — | — | US | disclosed |
| US-5891970-A | AMIDATION WITH 2-SULFOBENZOIC ANHYDRIDE | NATIONAL SCIENCE COUNCIL OF REPUBLIC OF CHINA (TW) | 1999-04-06 | — | — | US | disclosed |
| US-5462991-A | Pthalein-type | ROBOTTI KARLA M (US) | 1995-10-31 | — | — | US | disclosed |
| US-5384411-A | Phthalien dyes | HEWLETT-PACKARD COMPANY (US) | 1995-01-24 | — | — | US | disclosed |
| EP-0519198-A2 | Immobilization of PH-sensitive dyes to solid supports | Hewlett-Packard Company (US) | 1992-12-23 | — | — | EP | disclosed |
| US-3996202-A | Process for the preparation of sulfonate group containing aromatic polyamides | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093062-A1 | Fluorescent Dye Compounds, Conjugates and Uses Thereof | GFPT1, SLC46A1, SLC7A5 | CHEK1 3945/4885TTR 1843/4885PTPRC 3214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.