Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533533 | 0.90 | PIK3CA (0.31) | PIK3CAPRKDC | |
| SCHEMBL3765105 | 0.82 | GPR142 (0.33) | PIK3CAPRKDC | |
| SCHEMBL3757596 | 0.82 | PIK3CA (0.32) | PIK3CA | |
| SCHEMBL6118766 | 0.76 | CXCR3 (0.32) | — | |
| SCHEMBL855869 | 0.76 | PIK3CD (0.35) | — | |
| SCHEMBL16476907 | 0.74 | PTGER2 (0.32) | — | |
| SCHEMBL3764524 | 0.72 | CXCR3 (0.32) | — | |
| SCHEMBL855968 | 0.71 | GPR142 (0.33) | — | |
| SCHEMBL858896 | 0.71 | GSK3B (0.36) | — | |
| SCHEMBL3757514 | 0.71 | CXCR3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643315-A1 | BENZOXAZEPINES AS INHIBITORS OF P13K/mTOR AND METHODS OF THEIR USE AND MANUFACTURE | Exelixis, Inc. (US) | 2013-10-02 | — | — | EP | claimed |
| WO-2012071501-A1 | BENZOXAZEPINES ASN INHIBITORS OF P13K/M TOR AND METHODS OF THEIR USE AND MANUFACTURE | EXELIXIS, INC. (US) | 2012-05-31 | — | — | WO | claimed |