Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.75 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ALPI | P09923 | 1/20 | 0.59 |
| ▸ | ALPG | P10696 | 1/20 | 0.59 |
| ▸ | APEX1 | P27695 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2632218 | 0.94 | RAB9A (0.68) | RAB9ALMNASMN1; SMN2FFAR1CYP1A2 | |
| SCHEMBL10884944 | 0.92 | SMN1; SMN2 (0.88) | RAB9ALMNASMN1; SMN2FFAR1CYP1A2 | |
| Fenbufen SCHEMBL11329267 | 0.86 | SMN1; SMN2 (1.00) | RAB9ALMNASMN1; SMN2FFAR1CYP1A2 | |
| Fenbufen SCHEMBL25117 | 0.86 | SMN1; SMN2 (1.00) | RAB9ALMNASMN1; SMN2FFAR1CYP1A2 | |
| SCHEMBL10353454 | 0.85 | NR4A2 (0.81) | RAB9ALMNASMN1; SMN2FFAR1CYP1A2 | |
| SCHEMBL7939950 | 0.85 | NPC1 (0.81) | RAB9ALMNANPC1L3MBTL1ALDH1A1 | |
| Fenbufen SCHEMBL11393779 | 0.84 | SMN1; SMN2 (0.96) | RAB9ALMNASMN1; SMN2FFAR1CYP1A2 | |
| SCHEMBL8535224 | 0.83 | SMN1; SMN2 (0.72) | RAB9ALMNASMN1; SMN2FFAR1CYP1A2 | |
| SCHEMBL7857467 | 0.82 | KMT2A (0.89) | RAB9ALMNASMN1; SMN2FFAR1CYP1A2 | |
| SCHEMBL7864069 | 0.82 | SMN1; SMN2 (0.72) | RAB9ALMNASMN1; SMN2FFAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-4247466-A | 5-(4'-HYDROXY-4-BIPHENYLYL)-DIHYDRO-2(3H)-FURANEONE; ANTIINFLAMMATORY AGENTS; ANTICOAGULANTS | AMERICAN CYANAMID COMPANY (US) | 1981-01-27 | — | — | US | disclosed |