Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL448845 | 0.81 | TSHR (0.55) | ALDH1A1TSHR | |
| SCHEMBL28967081 | 0.78 | ALDH1A1 (0.51) | ALDH1A1TSHR | |
| SCHEMBL27728308 | 0.77 | TSHR (0.45) | ALDH1A1TSHR | |
| SCHEMBL28162516 | 0.76 | ALDH1A1 (0.44) | ALDH1A1TSHR | |
| SCHEMBL22026512 | 0.76 | TSHR (0.31) | TSHR | |
| SCHEMBL10010920 | 0.76 | TDP1 (0.32) | TSHR | |
| SCHEMBL28717782 | 0.73 | ALDH1A1 (0.64) | ALDH1A1TSHR | |
| SCHEMBL5889388 | 0.72 | ALDH1A1 (0.57) | ALDH1A1TSHR | |
| SCHEMBL4581116 | 0.72 | TSHR (0.52) | ALDH1A1TSHR | |
| SCHEMBL17350361 | 0.71 | ALDH1A1 (0.40) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854219-A | 9-N-ethenyl derivatives of 9(S)-erythromycylamine | PLIVA, FARMACEUTSKA, KEMIJSKA, PREHRAMBENA I KOZMETICKA INDUSTRIJA, DIONICKO DRUSTVO (HR) | 1998-12-29 | — | — | US | disclosed |
| EP-0838470-A1 | 9-N-ethenyl derivatives of 9(S)-erythromycylamine | PLIVA farmaceutska, kemijska, prehrambena i kozmeticka industrija, dionicko drustvo (HR) | 1998-04-29 | — | — | EP | disclosed |