SCHEMBL448845

SCHEMBL448845

C=C(C#N)C(=O)OC(C)CC

nearest known ligand 0.55

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.55
ALDH1A1 P00352 1/20 0.55
TP53 P04637 3/20 0.38
MAPT P10636 2/20 0.36
RXFP1 Q9HBX9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4581116 0.86 TSHR (0.52) TSHRALDH1A1
SCHEMBL15520224 0.85 ALDH1A1 (0.52) TSHRALDH1A1
SCHEMBL5889388 0.82 ALDH1A1 (0.57) TSHRALDH1A1
SCHEMBL1902715 0.82 ALDH1A1 (0.49) TSHRALDH1A1
SCHEMBL35728 0.81 ALDH1A1 (0.47) TSHRALDH1A1MAPT
SCHEMBL462000 0.81 ALDH1A1 (0.56) TSHRALDH1A1MAPT
SCHEMBL8533766 0.81 ALDH1A1 (0.52) TSHRALDH1A1
SCHEMBL15519572 0.81 TSHR (0.47) TSHRALDH1A1MAPT
SCHEMBL11799300 0.81 TSHR (0.55) TSHRALDH1A1
SCHEMBL4888140 0.80 ALDH1A1 (0.55) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026104704-A1 A COMBINATION, MEDICAL KIT AND MEDICAL DEVICE FOR TREATING AND/OR PREVENTING TISSUE LEAKAGE FUNDACIÓ INSTITUT DE INVESTIGACIÓ EN CIÈNCIES DE LA SALUT GERMANS TRIAS I PUJOL (ES) 2026-05-21 WO claimed
EP-4744687-A1 A COMBINATION, MEDICAL KIT AND MEDICAL DEVICE FOR TREATING AND/OR PREVENTING TISSUE LEAKAGE Aesculap AG (DE) 2026-05-20 EP claimed
EP-4717744-A1 USE OF A COMPOSITION BASED ON CYANOACRYLATE AND (METH)ACRYLATE Bostik SA (FR) 2026-04-01 EP claimed
US-20250215132-A1 TWO-PART CURABLE COMPOSITION BOSTIK SA (FR) 2025-07-03 US claimed
EP-4504844-A1 TWO-PART CURABLE COMPOSITION Bostik SA (FR) 2025-02-12 EP claimed
US-20240240064-A1 TWO-PART CURABLE COMPOSITION BOSTIK SA (FR) 2024-07-18 US claimed
EP-4334368-A1 TWO-PART CURABLE COMPOSITION Bostik SA (FR) 2024-03-13 EP claimed
CN-117377706-A Two-part curable composition 博斯蒂克股份公司 2024-01-09 CN claimed
WO-2023194367-A1 TWO-PART CURABLE COMPOSITION BOSTIK SA (FR) 2023-10-12 WO claimed
US-20230323137-A1 COMPOSITION FOR SEALING COATED ELECTRIC WIRE, AND COATED ELECTRIC WIRE TOAGOSEI CO. LTD. (JP) 2023-10-12 US claimed
US-6977278-B1 Cyanoacrylate compositions curable to flexible polymeric materials LOCTITE (R&D) LTD. (IE) 2005-12-20 US claimed
WO-2005006991-A2 DEVICE AND METHOD FOR FALLOPIAN TUBE OCCLUSION CHIROXIA LIMITED (IE) 2005-01-27 WO claimed
US-20040013614-A1 Acrylic-based adhesive composition BTG INTERNATIONAL LIMITED (GB) 2004-01-22 US claimed
EP-1360257-A1 CYANOACRYLATE COMPOSITIONS CURABLE TO FLEXIBLE POLYMERIC MATERIALS Loctite (R & D) Limited (IE) 2003-11-12 EP claimed
EP-1341563-A1 ACRYLIC-BASED ADHESIVE COMPOSITION UNIVERSIDAD DE ALICANTE (ES) 2003-09-10 EP claimed
WO-2002053666-A1 CYANOACRYLATE COMPOSITIONS CURABLE TO FLEXIBLE POLYMERIC MATERIALS LOCTITE (R & D) LIMITED (IE) 2002-07-11 WO claimed
WO-2002009784-A1 ACRYLIC-BASED ADHESIVE COMPOSITION UNIVERSIDAD DE ALICANTE (ES) 2002-02-07 WO claimed
US-5922783-A METALLOCENE, PHOTOINITIATOR, CYANOACRYLATE COMPONENT; REDUCED BLOOMING, CRAZING LOCTITE CORPORATION (US) 1999-07-13 US claimed
US-5530037-A COMBINATION OF AN ANIONIC STABILIZER AND A FREE-RADICAL STABILIZER; STORAGE STABILITY LOCTITE (IRELAND) LIMITED (IE) 1996-06-25 US claimed
US-5135784-A Wrapping web container and cutter for cutting wrapping web AYAKO OKUMURA (JP) 1992-08-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040013614-A1 Acrylic-based adhesive composition C5AR1, C1R, COL2A1 TSHR 459/4885ALDH1A1 980/4885TP53 3773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.