Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533856 | 0.89 | GPR119 (0.55) | GPR119 | |
| SCHEMBL9253174 | 0.81 | GPR119 (0.53) | GPR119 | |
| SCHEMBL9248533 | 0.80 | GPR119 (0.45) | GPR119 | |
| SCHEMBL8537262 | 0.75 | GPR119 (0.53) | GPR119 | |
| SCHEMBL9263416 | 0.74 | GPR119 (0.59) | GPR119 | |
| SCHEMBL9266545 | 0.74 | GPR119 (0.50) | GPR119 | |
| SCHEMBL11956857 | 0.74 | GPR119 (0.84) | GPR119 | |
| SCHEMBL8533540 | 0.74 | GPR119 (0.45) | GPR119 | |
| SCHEMBL15253175 | 0.74 | GPR119 (0.53) | GPR119 | |
| SCHEMBL9260951 | 0.72 | GPR119 (0.56) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643311-A1 | BICYCLIC GPR119 MODULATORS | Lupin Limited (IN) | 2013-10-02 | — | — | EP | disclosed |
| WO-2012069917-A1 | BICYCLIC GPR119 MODULATORS | LUPIN LIMITED (IN) | 2012-05-31 | — | — | WO | disclosed |