SCHEMBL9253174

SCHEMBL9253174

CC(C)OC(=O)N1CCC(Oc2ccc(-n3ccc4cc(NCCO)ccc43)nc2)CC1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 18/20 0.53
CHRNA7 P36544 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9254699 0.89 GPR119 (0.42) GPR119CHRNA7
SCHEMBL8535909 0.88 GPR119 (0.52) GPR119
SCHEMBL9263416 0.84 GPR119 (0.59) GPR119
SCHEMBL15253175 0.83 GPR119 (0.53) GPR119
SCHEMBL9267959 0.82 CHRNA7 (0.40) CHRNA7
SCHEMBL8531975 0.82 GPR119 (0.53) GPR119
SCHEMBL15253255 0.82 GPR119 (0.53) GPR119
SCHEMBL9253476 0.81 GPR119 (0.46) GPR119CHRNA7
SCHEMBL8533857 0.81 GPR119 (0.55) GPR119
SCHEMBL9259190 0.80 GPR119 (0.51) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012069917-A1 BICYCLIC GPR119 MODULATORS LUPIN LIMITED (IN) 2012-05-31 WO disclosed