SCHEMBL8533885

SCHEMBL8533885

CCCCCCCCCOc1ccccc1C1(C(=O)O)C=CC(c2ccc(OCC(C)CC)cc2)C=C1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.41
PLA2G4B P0C869 1/20 0.39
GPR88 Q9GZN0 3/20 0.38
FAAH O00519 12/20 0.37
MEN1 O00255 1/20 0.36
NR1I2 O75469 1/20 0.36
LMNA P02545 1/20 0.36
CHRM2 P08172 1/20 0.36
CYP3A4 P08684 1/20 0.36
ADRA2A P08913 1/20 0.36
MAPT P10636 1/20 0.36
OPRK1 P41145 1/20 0.36
HTR2B P41595 1/20 0.36
SLC6A3 Q01959 1/20 0.36
KMT2A Q03164 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
TP53 P04637 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5355707 0.91 TP53 (0.44) PLA2G4BFAAHMEN1NR1I2LMNA
SCHEMBL8376749 0.91 TP53 (0.44) PLA2G4BFAAHMEN1NR1I2LMNA
SCHEMBL6233132 0.84 PLA2G4B (0.39) PLA2G4BGPR88FAAHTP53TSHR
SCHEMBL9821354 0.79 FAAH (0.38) PLA2G4BFAAHTP53TSHR
SCHEMBL10773973 0.77 TP53 (0.41) PLA2G4BTP53TSHR
SCHEMBL10435817 0.77 TP53 (0.41) PLA2G4BTP53TSHR
SCHEMBL7780455 0.77 ALDH1A1 (0.51) PLA2G4BFAAHLMNATP53TSHR
SCHEMBL9155386 0.77 ALDH1A1 (0.48) PLA2G4BFAAHLMNATP53TSHR
SCHEMBL7778259 0.77 ALDH1A1 (0.51) PLA2G4BFAAHLMNATP53TSHR
SCHEMBL9615779 0.77 ALDH1A1 (0.51) PLA2G4BFAAHLMNATP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0387059-B1 Process of aligning liquid crystal media HERCULES INC (US) 1998-06-10 EP disclosed
US-5589100-A LIQUID CRYSTAL DISPLAY SUBSTRATES WITH ARYLAZO OR POLYARYLAZO DYES HERCULES INCORPORATED (US) 1996-12-31 US disclosed
US-5389285-A Liquid crystal coupled dichroic dyes HERCULES INCORPORATED (US) 1995-02-14 US disclosed
US-5326865-A Arylazo and poly(arylazo) dyes having at least one core radical selected from naphthyl or anthracyl and having at least one 2,3-dihydro-1,3-dialkyl perimidine substituent HERCULES INCORPORATED (US) 1994-07-05 US disclosed
EP-0460504-B1 Dichroic azo dyes HERCULES INC (US) 1994-04-27 EP disclosed
US-5097029-A Hydrolysis, alkylation, intermediates for azo dyes HERCULES INCORPORATED (US) 1992-03-17 US disclosed
EP-0460504-A1 Dichroic azo dyes HERCULES INCORPORATED (US) 1991-12-11 EP disclosed
US-5032009-A Polarized light exposure HERCULES INCORPORATED (US) 1991-07-16 US disclosed
EP-0432735-A2 Liquid crystal coupled dichroic dyes HERCULES INCORPORATED (US) 1991-06-19 EP disclosed
EP-0406812-A2 Process for the preparation of NiNi-dialkyl-1,8-naphthalene diamine HERCULES INCORPORATED (US) 1991-01-09 EP disclosed
US-4974941-A Process of aligning and realigning liquid crystal media HERCULES INCORPORATED (US) 1990-12-04 US disclosed
EP-0387059-A2 Process of aligning liquid crystal media HERCULES INCORPORATED (US) 1990-09-12 EP disclosed