Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537833 | 1.00 | MEN1 (0.40) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL1576747 | 0.98 | CES2 (0.39) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL2790873 | 0.95 | CES2 (0.42) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL2793665 | 0.95 | CES2 (0.42) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL10031351 | 0.91 | MEN1 (0.40) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL1576797 | 0.91 | — | — | |
| SCHEMBL871697 | 0.88 | CES2 (0.44) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL18246477 | 0.85 | MEN1 (0.46) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL2679547 | 0.85 | MEN1 (0.46) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL18245145 | 0.85 | MEN1 (0.46) | MEN1KMT2ATHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786493-A | SILYNATION OF UNSATURATED ALCOHOL, CYCLIZATION AND SOLVOLYSIS | HUELS AKTIENGESELLSCHAFT (DE) | 1998-07-28 | — | — | US | disclosed |