SCHEMBL8533937

SCHEMBL8533937

NC(=O)c1cc(N)ccc1C(=O)Nc1ccc(N)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
LMNA P02545 2/20 0.55
POLB P06746 2/20 0.55
PKM P14618 1/20 0.55
APEX1 P27695 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
KLKB1 P03952 1/20 0.54
JAK2 O60674 1/20 0.51
TYK2 P29597 1/20 0.51
MAPT P10636 4/20 0.50
RAB9A P51151 2/20 0.50
SNCA P37840 1/20 0.50
PTGS1 P23219 3/20 0.45
GFER P55789 2/20 0.45
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
F12 P00748 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9246171 0.93 MEN1 (0.55) MEN1KMT2ALMNAPOLBPKM
SCHEMBL2521357 0.84 KMT2A (0.56) MEN1KMT2ALMNAPOLBPKM
SCHEMBL6815337 0.83 ALDH1A1 (0.50) MEN1KMT2ALMNATDP1KLKB1
SCHEMBL17774881 0.81 P2RX1 (0.60) MEN1KMT2ALMNAPOLBPKM
SCHEMBL6315569 0.81 KLKB1 (0.77) MEN1KMT2ALMNAPOLBPKM
SCHEMBL8402954 0.80 KMT2A (0.64) MEN1KMT2ALMNAPOLBPKM
SCHEMBL10427105 0.79 KMT2A (0.59) MEN1KMT2ALMNAPOLBPKM
SCHEMBL29771741 0.79 KMT2A (0.59) MEN1KMT2ALMNAPOLBPKM
SCHEMBL14972555 0.79 KMT2A (0.55) MEN1KMT2ALMNAPOLBPKM
SCHEMBL29771755 0.79 KMT2A (0.55) MEN1KMT2ALMNAPOLBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6206856-A None JP disclosed
EP-0837896-A1 AROMATIC POLYAMIDE, OPTICAL ANISOTROPIC DOPE AND ARTICLES AND PREPARATION FOR THE SAME Kolon Industries Inc. (KR) 1998-04-29 EP disclosed
US-5728799-A FORMING A CONDENSATION POLYMER IN PYRIDINE FROM AROMATIC DIACID HALIDE AND AROMATIC DIAMINE TO FORM POLYAMIDE AND MIXTURE WITH A SALT TO FORM DOPE KOLON INDUSTRIES, INC. (KR) 1998-03-17 US disclosed
WO-1997003109-A1 AROMATIC POLYAMIDE, OPTICAL ANISOTROPIC DOPE AND ARTICLES AND PREPARATION FOR THE SAME KOLON INDUSTRIES, INC. (KR) 1997-01-30 WO disclosed
US-5380818-A High modulus aromatic polyamide film and production thereof KOLON INDUSTRIES, INC. (KR) 1995-01-10 US disclosed
JP-H06206856-A HIGHLY ELASTIC AROMATIC POLYAMIDE FILM AND PREPARATION THEREOF KOLON CO LTD 1994-07-26 JP disclosed