Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.44 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536250 | 0.83 | PTGES2 (0.46) | PTGES2CYP2D6CYP3A4SLC6A2SLC6A4 | |
| SCHEMBL10325728 | 0.77 | IDO1 (0.46) | PTGES2CYP2D6CYP3A4SLC6A2SLC6A4 | |
| SCHEMBL25774148 | 0.68 | ATAD2 (0.53) | ATAD2DAOKDM4ECYP1A2MAPT | |
| SCHEMBL23806232 | 0.67 | ATAD2 (0.49) | ATAD2DAOKDM4EPOLBIDH1 | |
| SCHEMBL19514185 | 0.67 | KDM5B (0.54) | ATAD2DAOKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL19231057 | 0.66 | KDM5A (0.55) | ATAD2DAOKDM4ETAAR1SMN1; SMN2 | |
| SCHEMBL30051860 | 0.65 | DAO (0.46) | ATAD2DAOKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL28235500 | 0.65 | DAO (0.49) | ATAD2DAOKDM4ECYP1A2MAPT | |
| SCHEMBL1587550 | 0.63 | DAO (0.47) | ATAD2DAOCYP1A2MAPTSMN1; SMN2 | |
| SCHEMBL13958698 | 0.63 | DAO (0.44) | ATAD2DAOMAPTSMN1; SMN2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135999-A1 | COMPOUNDS AND METHODS FOR ANTIVIRAL TREATMENT | PTC THERAPEUTICS, INC. (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135999-A1 | COMPOUNDS AND METHODS FOR ANTIVIRAL TREATMENT | EIF2AK2, MAVS, ZC3HAV1 | PTGES2 2477/4885ATAD2 2078/4885CYP2D6 3637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.