Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GGT1 | P19440 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531046 | 0.89 | MCL1 (0.51) | MCL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8531608 | 0.86 | MCL1 (0.46) | MCL1KDM4EHPGDMAPTSLC9A1 | |
| SCHEMBL8533967 | 0.84 | KDM4E (0.50) | MCL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8531587 | 0.79 | MCL1 (0.47) | MCL1AHRKDM4EALDH1A1HPGD | |
| SCHEMBL6996716 | 0.74 | ALB (0.47) | MCL1AHRKDM4EALDH1A1HPGD | |
| SCHEMBL6996712 | 0.74 | ALB (0.47) | MCL1AHRKDM4EALDH1A1HPGD | |
| SCHEMBL3275631 | 0.72 | MCL1 (0.65) | MCL1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8535826 | 0.70 | MCL1 (0.44) | MCL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5756844 | 0.70 | CFD (0.51) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL8532179 | 0.69 | MCL1 (0.47) | MCL1KDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728709-A | COAGULANTS AND ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-03-17 | — | — | US | disclosed |