Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1576702 | 0.92 | MAPT (0.59) | HTTSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL3607553 | 0.89 | RAB9A (0.55) | HTTSMN1; SMN2TSHRMAPTKMT2A | |
| SCHEMBL9661273 | 0.88 | POLB (0.53) | HTTSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL27501805 | 0.87 | MAPT (0.48) | HTTSMN1; SMN2TSHRMAPTKMT2A | |
| SCHEMBL10386794 | 0.87 | HTT (0.51) | HTTSMN1; SMN2TSHRMAPTKMT2A | |
| SCHEMBL10747680 | 0.85 | KMT2A (0.43) | HTTSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL30925086 | 0.84 | MAPT (0.49) | HTTSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL27424384 | 0.83 | KMT2A (0.53) | HTTSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL9368434 | 0.82 | CYP1A2 (0.59) | HTTSMN1; SMN2TSHRMAPTKMT2A | |
| SCHEMBL8447590 | 0.82 | KDM4E (0.48) | HTTSMN1; SMN2MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642791-A | Sulfonylurea compound, preparation method thereof and application thereof in preparing herbicide | 南开大学 | 2020-01-03 | — | — | CN | claimed |
| EP-0394194-B1 | PROTECTED AMINO-ACIDS AND PROCESS FOR THEIR PREPARATION | CALBIOCHEM-NOVABIOCHEM AG (CH) | 1993-08-18 | — | — | EP | claimed |
| JP-1038089-A | — | — | None | — | — | JP | disclosed |
| CN-114456120-B | Bissulfonylamino substituted sulfonylurea compound, and preparation method and application thereof | 郑州手性药物研究院有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-117903066-A | Benzene ring alkoxy substituted sulfonylurea compound and application thereof in preparation of selective herbicide | 南开大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-110642791-B | Sulfonylurea compound, preparation method thereof and application thereof in preparing herbicide | 南开大学 | 2022-06-28 | — | — | CN | disclosed |
| CN-110642791-A | Sulfonylurea compound, preparation method thereof and application thereof in preparing herbicide | 南开大学 | 2020-01-03 | — | — | CN | disclosed |
| EP-0467251-B1 | Process for the preparation of N-alkylsulfonylaminosulfonyl ureas | HOECHST SCHERING AGREVO GMBH (DE) | 1998-06-03 | — | — | EP | disclosed |
| EP-0238070-B1 | Sulfonylurea compounds, their production and herbicidal use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-29 | — | — | EP | disclosed |
| US-5155222-A | PROCESS FOR THE PREPARATION OF N-ALKYLSULFONYLAMINOSULFONYLUREAS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-13 | — | — | US | disclosed |
| EP-0234352-B1 | SULFONAMIDE COMPOUNDS AND SALTS THEREOF, HERBICIDAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR PRODUCING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1992-04-29 | — | — | EP | disclosed |
| US-4743290-A | Thiophenesulfonamide herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-05-10 | — | — | US | disclosed |
| EP-0238070-A2 | Sulfonylurea compounds, their production and herbicidal use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-23 | — | — | EP | disclosed |
| EP-0234352-A1 | Sulfonamide compounds and salts thereof, herbicidal compositions containing them, and process for producing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1987-09-02 | — | — | EP | disclosed |
| US-4677217-A | CHEMICAL INTERMEDIATES FOR HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1987-06-30 | — | — | US | disclosed |
| EP-0212779-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-03-04 | — | — | EP | disclosed |
| EP-0207609-A1 | Herbicidal thiophenesulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-01-07 | — | — | EP | disclosed |
| US-4602936-A | Herbicidal sulfonylureas | CIBA-GEIGY CORPORATION (US) | 1986-07-29 | — | — | US | disclosed |
| US-4559078-A | POSTEMERGENCE AND PREEMERGENCE HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1985-12-17 | — | — | US | disclosed |
| EP-0164017-A2 | Substituted phenyl sulfonyl ureas | BAYER AG (DE) | 1985-12-11 | — | — | EP | disclosed |