Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | F12 | P00748 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27424384 | 0.91 | KMT2A (0.53) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| SCHEMBL8533974 | 0.89 | HTT (0.53) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| SCHEMBL27539734 | 0.87 | RAB9A (0.47) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| SCHEMBL27457032 | 0.87 | SLC2A1 (0.57) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| SCHEMBL7244914 | 0.86 | ALDH1A1 (0.56) | RAB9AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27545158 | 0.85 | ALDH1A1 (0.53) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| SCHEMBL18029688 | 0.85 | F2 (0.43) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| SCHEMBL29700251 | 0.85 | F2 (0.43) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| SCHEMBL10747680 | 0.84 | KMT2A (0.43) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| SCHEMBL23240069 | 0.84 | ALDH1A1 (0.59) | RAB9AALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118754874-A | Trifluidine Synthesis method of sulfosulfuron | 河北八亿时空药业有限公司 | 2024-10-11 | — | — | CN | disclosed |
| US-11845715-B2 | — | — | 2023-12-19 | — | — | US | disclosed |
| US-11845715-B2 | — | — | 2023-12-19 | — | — | US | disclosed |
| US-11560391-B2 | Sulfonylurea compounds as inhibitors of interleukin-1 activity | GENENTECH, INC. (US) | 2023-01-24 | — | — | US | disclosed |
| US-20220112159-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | UNIV QUEENSLAND (AU) | 2022-04-14 | — | — | US | disclosed |
| EP-3888749-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | The University of Queensland (AU) | 2021-10-06 | — | — | EP | disclosed |
| US-11130731-B2 | Sulfonylureas and related compounds and use of same | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2021-09-28 | — | — | US | disclosed |
| WO-2020018970-A1 | SULFONYLUREA COMPOUNDS AS INHIBITORS OF INTERLEUKIN-1 ACTIVITY | GENENTECH, INC. (US) | 2020-01-23 | — | — | WO | disclosed |
| EP-3578547-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | The University of Queensland (AU) | 2019-12-11 | — | — | EP | disclosed |
| US-20180044287-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | INFLAZOME LIMITED (IE) | 2018-02-15 | — | — | US | disclosed |
| EP-0238070-B1 | Sulfonylurea compounds, their production and herbicidal use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-29 | — | — | EP | disclosed |
| CN-1018643-B | Process for producing sulfonylurea compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1992-10-14 | — | — | CN | disclosed |
| EP-0494973-A1 | COMPOUNDS USEFUL FOR MEASURING LOW LEVELS OF SULFONYLUREAS BY IMMUNOASSAY | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-07-22 | — | — | EP | disclosed |
| CN-1059073-A | Solsonylurea compounds is as the purposes of weed killer herbicide | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1992-03-04 | — | — | CN | disclosed |
| US-5084086-A | Triazinyl or pyrimidinyl sulfonylureas as herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-01-28 | — | — | US | disclosed |
| WO-1991015478-A1 | CROP-SELECTIVE HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-17 | — | — | WO | disclosed |
| US-5017212-A | For rice paddies | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| WO-1991004967-A1 | COMPOUNDS USEFUL FOR MEASURING LOW LEVELS OF SULFONYLUREAS BY IMMUNOASSAY | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-18 | — | — | WO | disclosed |
| CN-87102123-A | Sulfonylurea compounds, their preparation and their use as herbicides | — | 1987-10-21 | — | — | CN | disclosed |
| EP-0238070-A2 | Sulfonylurea compounds, their production and herbicidal use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220112159-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | NLRP3, PYCARD, IAPP | RAB9A 3614/4885NPC1 799/4885ALDH1A1 3558/4885 |
| US-11845715-B2 | — | NLRP3, PYCARD, NOD1 | RAB9A 3413/4885NPC1 255/4885ALDH1A1 3407/4885 |
| US-11130731-B2 | Sulfonylureas and related compounds and use of same | NLRP3, PYCARD, IAPP | RAB9A 3614/4885NPC1 799/4885ALDH1A1 3558/4885 |
| US-11560391-B2 | Sulfonylurea compounds as inhibitors of interleukin-1 activity | IL1B, IL1A, IL18 | RAB9A 2544/4885NPC1 750/4885ALDH1A1 1315/4885 |
| US-20180044287-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | NLRP3, PYCARD, IAPP | RAB9A 3614/4885NPC1 799/4885ALDH1A1 3558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.