Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701311 | 0.86 | — | — | |
| SCHEMBL5390731 | 0.86 | FDPS (0.43) | LMNASLC22A6ALOX5ITGB3ITGA2B | |
| SCHEMBL5940333 | 0.86 | FDPS (0.43) | LMNASLC22A6ALOX5ITGB3ITGA2B | |
| SCHEMBL3441767 | 0.84 | FDPS (0.50) | LMNATSHRMEN1ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL701182 | 0.83 | FDPS (0.49) | LMNATSHRMEN1ALDH1A1POLB | |
| SCHEMBL5499952 | 0.83 | FDPS (0.49) | LMNATSHRMEN1ALDH1A1POLB | |
| SCHEMBL3102769 | 0.82 | — | — | |
| SCHEMBL26548658 | 0.80 | LMNA (0.42) | LMNATSHRPMP22NFKB1ITGB3 | |
| SCHEMBL6050153 | 0.79 | FDPS (0.49) | LMNATSHRPMP22HSD17B10CYP2C9 | |
| SCHEMBL11847852 | 0.79 | LMNA (0.43) | LMNATSHRPMP22NFKB1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0504612-B1 | Novel 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID CO (US) | 1998-01-21 | — | — | EP | disclosed |
| US-5700930-A | 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1997-12-23 | — | — | US | disclosed |
| US-5656753-A | 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1997-08-12 | — | — | US | disclosed |
| US-5371215-A | 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1994-12-06 | — | — | US | disclosed |
| US-5189158-A | 4-SUBSTITUTED AZETIDINONES AS PRECURSORS TO 2-SUBSTITUTED-3-CARBOXY CARBAPENEM ANTIBIOTICS AND A METHOD OF PRODUCING THEM | AMERICAN CYANAMID COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0504612-A2 | Novel 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1992-09-23 | — | — | EP | disclosed |