Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.56 |
| ▸ | TERT | O14746 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28470846 | 0.82 | MTNR1A (0.55) | MTNR1AMTNR1BTERTCES2CES1 | |
| SCHEMBL11657930 | 0.81 | MTNR1A (0.51) | MTNR1AMTNR1BTERTCES2CES1 | |
| SCHEMBL11663550 | 0.81 | MTNR1A (0.48) | MTNR1AMTNR1BTERTCES2CES1 | |
| SCHEMBL11663641 | 0.81 | MTNR1B (0.55) | MTNR1AMTNR1BTERT | |
| SCHEMBL2331824 | 0.80 | NPC1 (0.50) | MTNR1AMTNR1BLMNA | |
| SCHEMBL11663805 | 0.79 | MTNR1A (0.53) | MTNR1AMTNR1BLMNA | |
| SCHEMBL11661819 | 0.79 | MTNR1A (0.56) | MTNR1AMTNR1B | |
| SCHEMBL11658674 | 0.78 | MTNR1A (0.56) | MTNR1AMTNR1BTERTCES2CES1 | |
| SCHEMBL11665110 | 0.77 | MTNR1B (0.51) | MTNR1AMTNR1BTERT | |
| SCHEMBL11664538 | 0.77 | MTNR1A (0.59) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |