Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16624359 | 0.92 | DHFR (0.34) | TLR7DHFR | |
| SCHEMBL3703402 | 0.88 | TLR7 (0.41) | TLR7 | |
| SCHEMBL16616829 | 0.88 | TLR7 (0.39) | TLR7 | |
| SCHEMBL16617074 | 0.88 | TLR7 (0.45) | TLR7 | |
| SCHEMBL4203291 | 0.86 | TLR7 (0.39) | TLR7 | |
| SCHEMBL3705863 | 0.81 | TLR7 (0.43) | TLR7DHFR | |
| SCHEMBL3705698 | 0.80 | TLR7 (0.39) | TLR7 | |
| SCHEMBL15302923 | 0.80 | TLR7 (0.38) | TLR7 | |
| SCHEMBL16624357 | 0.80 | DHFR (0.33) | TLR7DHFR | |
| SCHEMBL16624356 | 0.79 | TLR7 (0.37) | TLR7DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12077510-B2 | Carboxylic acid compounds | Sumitomo Pharma Co., Ltd. (JP) | 2024-09-03 | — | — | US | disclosed |
| US-20220267282-A1 | CARBOXYLIC ACID COMPOUNDS | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2022-08-25 | — | — | US | disclosed |
| US-11299465-B2 | Carboxylic acid compounds | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2022-04-12 | — | — | US | disclosed |
| US-20200317623-A1 | CARBOXYLIC ACID COMPOUNDS | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-10-08 | — | — | US | disclosed |
| US-10562861-B2 | Carboxylic acid compounds | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-02-18 | — | — | US | disclosed |
| US-20190119220-A1 | CARBOXYLIC ACID COMPOUNDS | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2019-04-25 | — | — | US | disclosed |
| US-10150743-B2 | Carboxylic acid compounds | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2018-12-11 | — | — | US | disclosed |
| EP-2850067-B1 | CARBOXYLIC ACID COMPOUNDS | SUMITOMO DAINIPPON PHARMA CO LTD (JP) | 2017-08-16 | — | — | EP | disclosed |
| EP-2432768-B1 | NOVEL PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER AND FURTHER DISEASES | SUMITOMO DAINIPPON PHARMA CO LTD (JP) | 2017-07-05 | — | — | EP | disclosed |
| US-9533978-B2 | Pyrimidine derivatives and their use in the treatment of cancer and further diseases | SUMITOMO DAINIPPON PHARMA CO., LTD (JP) | 2017-01-03 | — | — | US | disclosed |
| US-20160251319-A1 | CARBOXYLIC ACID COMPOUNDS | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2016-09-01 | — | — | US | disclosed |
| US-9376398-B2 | Carboxylic acid compounds | SUMITOMO DAINIPPON PHARMA CO., LTD (JP) | 2016-06-28 | — | — | US | disclosed |
| US-20150099770-A1 | CARBOXYLIC ACID COMPOUNDS | Sumitomo Pharma Co., Ltd. (JP) | 2015-04-09 | — | — | US | disclosed |
| US-20150080396-A1 | Novel Pyrimidine Derivatives and Their Use in the Treatment of Cancer and Further Diseases | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2015-03-19 | — | — | US | disclosed |
| WO-2012066335-A1 | PHENOL COMPOUNDS ALS TOLL -LIKE RECEPTOR 7 AGONISTS | ASTRAZENECA AB (SE) | 2012-05-24 | — | — | WO | disclosed |
| US-20120122867-A1 | NOVEL PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER AND FURTHER DISEASES | ASTRAZENECA UK LIMITED (GB) | 2012-05-17 | — | — | US | disclosed |
| EP-2432768-A1 | NOVEL PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER AND FURTHER DISEASES | AstraZeneca AB (SE) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133885-A1 | NOVEL PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER AND FURTHER DISEASES | ASTRAZENECA AB (SE) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099770-A1 | CARBOXYLIC ACID COMPOUNDS | C9, SUCNR1, C3AR1 | TLR7 87/4885DHFR 1267/4885 |
| US-20160251319-A1 | CARBOXYLIC ACID COMPOUNDS | C9, SUCNR1, C3AR1 | TLR7 87/4885DHFR 1267/4885 |
| US-20120122867-A1 | NOVEL PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER AND FURTHER DISEASES | TYMS, TYMP, DPYD | TLR7 2123/4885DHFR 19/4885 |
| US-10150743-B2 | Carboxylic acid compounds | C9, C3AR1, SUCNR1 | TLR7 79/4885DHFR 1434/4885 |
| US-12077510-B2 | Carboxylic acid compounds | C9, C3AR1, SUCNR1 | TLR7 79/4885DHFR 1434/4885 |
| US-20200317623-A1 | CARBOXYLIC ACID COMPOUNDS | C9, C3AR1, SUCNR1 | TLR7 79/4885DHFR 1434/4885 |
| US-20190119220-A1 | CARBOXYLIC ACID COMPOUNDS | C9, C3AR1, SUCNR1 | TLR7 79/4885DHFR 1434/4885 |
| US-11299465-B2 | Carboxylic acid compounds | C9, C3AR1, SUCNR1 | TLR7 79/4885DHFR 1434/4885 |
| US-20150080396-A1 | Novel Pyrimidine Derivatives and Their Use in the Treatment of Cancer and Further Diseases | TYMS, TYMP, DPYD | TLR7 2123/4885DHFR 19/4885 |
| US-20220267282-A1 | CARBOXYLIC ACID COMPOUNDS | C9, C3AR1, SUCNR1 | TLR7 79/4885DHFR 1434/4885 |
| US-10562861-B2 | Carboxylic acid compounds | C9, C3AR1, SUCNR1 | TLR7 79/4885DHFR 1434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.