Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | TCF4 | P15884 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 2/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | SDHB | P21912 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539308 | 0.86 | TDP1 (0.49) | CA12CA1CA2CA9HSD17B10 | |
| SCHEMBL8537635 | 0.80 | MAOB (0.47) | HSD17B10ACLYTDP1 | |
| SCHEMBL26572779 | 0.78 | S1PR4 (0.49) | CA12CA1CA2CA9TCF4 | |
| SCHEMBL8539116 | 0.78 | HSP90AA1 (0.45) | CA1CA2CA9SDHBHSD17B10 | |
| SCHEMBL31091675 | 0.77 | ERN1 (0.51) | CA12CA1CA2CA9S1PR4 | |
| SCHEMBL31091678 | 0.77 | ERN1 (0.51) | CA12CA1CA2CA9S1PR4 | |
| SCHEMBL13953925 | 0.75 | CYP46A1 (0.61) | CA12CA1CA2CA9TCF4 | |
| SCHEMBL16601618 | 0.74 | CA12 (0.54) | CA12CA1CA2CA9TCF4 | |
| SCHEMBL7719381 | 0.74 | CA12 (0.59) | CA12CA1CA2CA9ERN1 | |
| SCHEMBL30285148 | 0.74 | CA12 (0.59) | CA12CA1CA2CA9ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |