Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536322 | 0.87 | MAOB (0.44) | MAOBALKBH3ACHEALDH1A1SMN1; SMN2 | |
| SCHEMBL2315622 | 0.83 | MAOB (0.49) | MAOBALKBH3ACHEALDH1A1SMN1; SMN2 | |
| SCHEMBL8534267 | 0.80 | CA12 (0.47) | ACLYHSD17B10TDP1 | |
| SCHEMBL277912 | 0.75 | ACHE (0.57) | MAOBALKBH3ACHEALDH1A1SMN1; SMN2 | |
| SCHEMBL30728871 | 0.73 | ACHE (0.55) | MAOBALKBH3ACHEALDH1A1SMN1; SMN2 | |
| SCHEMBL7875685 | 0.73 | ACHE (0.55) | MAOBALKBH3ACHEALDH1A1SMN1; SMN2 | |
| SCHEMBL8538998 | 0.73 | GSTP1 (0.51) | MAOBSMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL24061160 | 0.72 | ACHE (0.53) | MAOBALKBH3ACHEALDH1A1SMN1; SMN2 | |
| SCHEMBL18087561 | 0.72 | ACHE (0.53) | MAOBALKBH3ACHEALDH1A1SMN1; SMN2 | |
| SCHEMBL8539259 | 0.72 | ALKBH3 (0.44) | MAOBALKBH3ACHEALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |