Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534267 | 0.86 | CA12 (0.47) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL6166229 | 0.81 | HPGD (0.48) | TDP1HPGDLMNACA12CA1 | |
| SCHEMBL8539116 | 0.78 | HSP90AA1 (0.45) | HPGDLMNACA1CA2CA9 | |
| SCHEMBL19111160 | 0.74 | EGFR (0.68) | TDP1HPGDLMNACA12CA1 | |
| SCHEMBL26571944 | 0.74 | TDP1 (0.61) | TDP1HPGDLMNACA12CA1 | |
| SCHEMBL2622515 | 0.73 | ACR (0.48) | TDP1HPGDLMNACA12CA1 | |
| SCHEMBL8537635 | 0.72 | MAOB (0.47) | TDP1HPGDLMNAALDH1A1MAPT | |
| SCHEMBL8538998 | 0.72 | GSTP1 (0.51) | HPGDCA12CA1CA2CA9 | |
| SCHEMBL361378 | 0.72 | PTGS2 (0.53) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL12714432 | 0.72 | TDP1 (0.58) | TDP1HPGDLMNACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |