Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RHEB | Q15382 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BID | P55957 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535826 | 0.83 | MCL1 (0.44) | MCL1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL8534428 | 0.80 | SRD5A2 (0.57) | SRD5A2SRD5A1MCL1MEN1KMT2A | |
| SCHEMBL8532366 | 0.74 | MCL1 (0.53) | MCL1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL6989039 | 0.73 | ALB (0.43) | SRD5A2SRD5A1MAPTMAPK1TDP1 | |
| SCHEMBL6989042 | 0.73 | ALB (0.43) | SRD5A2SRD5A1MAPTMAPK1TDP1 | |
| SCHEMBL8531046 | 0.72 | MCL1 (0.51) | MCL1MAPTTDP1MEN1KMT2A | |
| SCHEMBL3275631 | 0.72 | MCL1 (0.65) | MCL1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL8531587 | 0.69 | MCL1 (0.47) | MCL1MAPTMEN1KMT2A | |
| SCHEMBL11643569 | 0.68 | MAPT (0.64) | MAPTMAPK1TDP1L3MBTL1MEN1 | |
| SCHEMBL7050350 | 0.68 | PTGER1 (0.61) | SRD5A2MCL1MAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728709-A | COAGULANTS AND ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-03-17 | — | — | US | disclosed |