Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534337 | 0.83 | SRD5A2 (0.46) | MCL1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL8532179 | 0.82 | MCL1 (0.47) | MCL1NPC1RAB9ASLC9A1MAPT | |
| SCHEMBL8532366 | 0.79 | MCL1 (0.53) | MCL1NPC1RAB9ASLC9A1MAPT | |
| SCHEMBL8531046 | 0.77 | MCL1 (0.51) | MCL1NPC1RAB9ASLC9A1MAPT | |
| SCHEMBL3275631 | 0.77 | MCL1 (0.65) | MCL1NPC1RAB9ASLC9A1MAPT | |
| SCHEMBL8531587 | 0.74 | MCL1 (0.47) | MCL1SLC9A1MAPTDAOKDM4E | |
| SCHEMBL8530744 | 0.71 | MCL1 (0.47) | MCL1SLC9A1MAPTDAOKDM4E | |
| SCHEMBL8534277 | 0.70 | MCL1 (0.46) | MCL1SLC9A1MAPTKDM4EALDH1A1 | |
| SCHEMBL6988897 | 0.69 | ABL1 (0.51) | NPC1ALOX5GAAPKMRAB9A | |
| SCHEMBL6988902 | 0.69 | ABL1 (0.51) | NPC1ALOX5GAAPKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728709-A | COAGULANTS AND ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-03-17 | — | — | US | disclosed |